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Advisor(s)
Abstract(s)
The nuclear receptor retinoid X receptor (RXR) belongs to a nuclear receptor superfamily that modulates diverse functions via homodimerization with itself or several other nuclear receptors, including PPARα. While the activation of PPARα by natural or synthetic agonists regulates the sleep-wake cycle, the role of RXR in the sleep modulation is unknown.
Description
Keywords
Adenosine Dopamine Retinoid X receptor Serotonin Sleep
Citation
Murillo-Rodríguez E, Millán-Aldaco D, Arankowsky-Sandoval G, Yamamoto T, Cid L, Monteiro D, Rocha NB, Telles-Correia D, Teixeira DS, Veras AB, Budde H, Machado S, Imperatori C, Torterolo P. The retinoid X receptor: a nuclear receptor that modulates the sleep-wake cycle in rats. Psychopharmacology (Berl). 2020 Jul;237(7):2055-2073. doi: 10.1007/s00213-020-05518-8. Epub 2020 May 30. PMID: 32472163.