Publication
Fast Estimation of the Spectral Optical Properties of Rabbit Pancreas and Pigment Content Analysis
| dc.contributor.author | Martins, Inês Soraia | |
| dc.contributor.author | Silva, Hugo Filipe | |
| dc.contributor.author | Tuchin, Valery Victorovich | |
| dc.contributor.author | Oliveira, Luís Manuel | |
| dc.date.accessioned | 2023-02-14T09:29:12Z | |
| dc.date.available | 2023-02-14T09:29:12Z | |
| dc.date.issued | 2022 | |
| dc.description.abstract | The pancreas is a highly important organ, since it produces insulin and prevents the occurrence of diabetes. Although rare, pancreatic cancer is highly lethal, with a small life expectancy after being diagnosed. The pancreas is one of the organs less studied in the field of biophotonics. With the objective of acquiring information that can be used in the development of future applications to diagnose and treat pancreas diseases, the spectral optical properties of the rabbit pancreas were evaluated in a broad-spectral range, between 200 and 1000 nm. The method used to obtain such optical properties is simple, based almost on direct calculations from spectral measurements. The optical properties obtained show similar wavelength dependencies to the ones obtained for other tissues, but a further analysis on the spectral absorption coefficient showed that the pancreas tissues contain pigments, namely melanin, and lipofuscin. Using a simple calculation, it was possible to retrieve similar contents of these pigments from the absorption spectrum of the pancreas, which indicates that they accumulate in the same proportion as a result of the aging process. Such pigment accumulation was camouflaging the real contents of DNA, hemoglobin, and water, which were precisely evaluated after subtracting the pigment absorption. | pt_PT |
| dc.description.sponsorship | The work of I.S.M. was supported by the Portuguese Science Foundation, grant no. FCTUIDB/ 151528/2021. The work of H.F.S and L.M.O. was supported by the Portuguese Science Foundation, grant No. FCT-UIDB/04730/2020. The work of V.V.T. was supported by a grant under the Decree of the Government of the Russian Federation No. 220 of 09 April 2010 (Agreement No. 075-15-2021-615 of 4 June 2021). | |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.doi | 10.3390/photonics9020122 | pt_PT |
| dc.identifier.uri | http://hdl.handle.net/10400.22/22262 | |
| dc.language.iso | eng | pt_PT |
| dc.publisher | MDPI | pt_PT |
| dc.relation | UIDB/151528/2021 | |
| dc.relation | Center for Innovation in Industrial Engineering and Technology | |
| dc.relation.publisherversion | https://www.mdpi.com/2304-6732/9/2/122 | pt_PT |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | pt_PT |
| dc.subject | Pancreas tissue | pt_PT |
| dc.subject | Optical properties | pt_PT |
| dc.subject | Scattering coefficient | pt_PT |
| dc.subject | Absorption coefficient | pt_PT |
| dc.subject | Pigment detection | pt_PT |
| dc.title | Fast Estimation of the Spectral Optical Properties of Rabbit Pancreas and Pigment Content Analysis | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.awardTitle | Center for Innovation in Industrial Engineering and Technology | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04730%2F2020/PT | |
| oaire.citation.issue | 2 | pt_PT |
| oaire.citation.startPage | 122 | pt_PT |
| oaire.citation.title | Photonics | pt_PT |
| oaire.citation.volume | 9 | pt_PT |
| oaire.fundingStream | 6817 - DCRRNI ID | |
| person.familyName | Oliveira | |
| person.givenName | Luís | |
| person.identifier | 414820 | |
| person.identifier.ciencia-id | C312-F342-BD23 | |
| person.identifier.orcid | 0000-0003-0667-3428 | |
| person.identifier.rid | B-7198-2017 | |
| person.identifier.scopus-author-id | 55853723900 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | article | pt_PT |
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