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Comparison of Radiotherapy techniques for left-sided early-stage breast cancer Radiotherapy: A systematic literature review on planning dose analysis

dc.contributor.authorCosta, Fernando M.
dc.contributor.authorOliveira-Sousa, Rúben
dc.contributor.authorPinto, Gabriela
dc.contributor.authorMeireles, Pedro
dc.contributor.authorMonteiro, Armanda
dc.contributor.authorFaria, Isabel
dc.contributor.authorPiñeiro, Manuel M.
dc.contributor.authorCouto, J. Guilherme
dc.contributor.authorSousa Pinho Faria, Isabel Maria
dc.date.accessioned2026-05-12T13:01:46Z
dc.date.available2026-05-12T13:01:46Z
dc.date.issued2025-10-18
dc.description.abstractAdjuvant radiotherapy improves local cancer control and the overall survival of women with breast cancer. However, it is unclear what the ideal radiotherapy (RT) planning technique is for these patients. The aim was to perform a synopsis of the literature comparing RT techniques to treat early-stage left breast tumours. A PRISMA guideline was used on this systematic review and registered in PROSPERO (CRD420251168901). For all the investigations, the Open-field technique (OF) showed worse results for the Planning Target Volume (PTV), lung and heart. Field-in-Field stood out in low doses and mean doses in OARs. IMRT distinguished itself in Homogeneity Index. VMAT provides higher Conformity Index results and thus an advantage in high and mean doses of OARs. Hybrid-IMRT and Hybrid-VMAT combine the advantages of two techniques; however, few studies have included them in their research. There is not a clear “gold-standard” technique, and the results depend heavily on many factors which affect the quality of the plans and the priorities of the departments. However, OF is no longer recommended. An international framework should be developed to allow for a standardisation of the plans, improving inter-departmental comparisons. And each department should perform their own comparison between the techniques available to them.eng
dc.identifier.citationCosta, F. M., Oliveira-Sousa, R., Pinto, G., Meireles, P., Monteiro, A., Faria, I., Piñeiro, M. M., & Couto, J. G. (2025). Comparison of Radiotherapy Techniques for Left-Sided Early-Stage Breast Cancer Radiotherapy: A Systematic Literature Review on Planning Dose Analysis. Applied Sciences, 15(20), 11187. https://doi.org/10.3390/app152011187
dc.identifier.doi10.3390/app152011187
dc.identifier.eissn2076-3417
dc.identifier.urihttp://hdl.handle.net/10400.22/32349
dc.language.isoeng
dc.peerreviewedyes
dc.publisherMDPI
dc.relation.hasversionhttps://www.mdpi.com/2076-3417/15/20/11187
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectLeft-sided early-stage breast cancer
dc.subjectRadiotherapy
dc.subjectDosimetric technique
dc.subjectSystematic literature review
dc.titleComparison of Radiotherapy techniques for left-sided early-stage breast cancer Radiotherapy: A systematic literature review on planning dose analysiseng
dc.typeresearch article
dspace.entity.typePublication
oaire.citation.issue20
oaire.citation.titleApplied Sciences
oaire.citation.volume15
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameSousa Pinho Faria
person.givenNameIsabel Maria
person.identifier.orcid0000-0002-1467-7800
relation.isAuthorOfPublicationb74bdeca-0113-40a8-ba5a-8fe2d558fe0e
relation.isAuthorOfPublication.latestForDiscoveryb74bdeca-0113-40a8-ba5a-8fe2d558fe0e

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