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Noncoplanar beam angle optimization in IMRT treatment planning using pattern search methods

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dc.contributor.authorRocha, Humberto
dc.contributor.authorDias, Joana M
dc.contributor.authorCosta Ferreira, Brigida
dc.contributor.authorLopes, Maria C
dc.date.accessioned2019-05-22T15:21:19Z
dc.date.available2019-05-22T15:21:19Z
dc.date.issued2015
dc.description.abstractRadiation therapy is used to treat localized cancers, aiming to deliver a dose of radiation to the tumor volume to sterilize all cancer cells while minimizing the collateral effects on the surrounding healthy organs and tissues. The planning of radiation therapy treatments requires decisions regarding the angles used for radiation incidence, the fluence intensities and, if multileaf collimators are used, the definition of the leaf sequencing. The beam angle optimization problem consists in finding the optimal number and incidence directions of the irradiation beams. The selection of appropriate radiation incidence directions is important for the quality of the treatment. However, the possibility of improving the quality of treatment plans by an optimized selection of the beam incidences is seldom done in the clinical practice. Adding the possibility for noncoplanar incidences is even more rarely used. Nevertheless, the advantage of noncoplanar beams is well known. The optimization of noncoplanar beam incidences may further allow the reduction of the number of beams needed to reach a clinically acceptable plan. In this paper we present the benefits of using pattern search methods for the optimization of the highly non-convex noncoplanar beam angle optimization problem.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1088/1742-6596/616/1/012014pt_PT
dc.identifier.issn1742-6588
dc.identifier.urihttp://hdl.handle.net/10400.22/13777
dc.language.isoengpt_PT
dc.relationCENTRO07-0224-FEDER-002003pt_PT
dc.relationPEst-OE/EEI/UI308/2014pt_PT
dc.relation.publisherversionhttps://iopscience.iop.org/article/10.1088/1742-6596/616/1/012014/pdfpt_PT
dc.subjectRadiation therapypt_PT
dc.subjectcancer cellspt_PT
dc.subjectnoncoplanar incidencespt_PT
dc.titleNoncoplanar beam angle optimization in IMRT treatment planning using pattern search methodspt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/COMPETE/PTDC%2FEIA-CCO%2F121450%2F2010/PT
oaire.citation.startPage012014pt_PT
oaire.citation.titleJournal of Physics: Conference Seriespt_PT
oaire.citation.volume616pt_PT
oaire.fundingStreamCOMPETE
person.familyNameCosta Ferreira
person.givenNameBrigida
person.identifier1167997
person.identifier.ciencia-idA61B-E07B-84B3
person.identifier.orcid0000-0001-7988-7545
person.identifier.scopus-author-id14050253300
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT
relation.isAuthorOfPublicationeac8b2c3-0ef3-48f5-a3c7-8ca796a098ae
relation.isAuthorOfPublication.latestForDiscoveryeac8b2c3-0ef3-48f5-a3c7-8ca796a098ae
relation.isProjectOfPublication5d657eed-3fe3-4b0f-92d0-0bc8759bfcd8
relation.isProjectOfPublication.latestForDiscovery5d657eed-3fe3-4b0f-92d0-0bc8759bfcd8

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