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Authors
Advisor(s)
Abstract(s)
The auditory N1 component has been gaining interest as a possible biomarker in schizophrenia (SCZ). N1 to right (RE) and left ear (LE) amplitudes and latencies were assessed using a monoaural auditory oddball paradigm in 12 SCZ subjects and 15 matched healthy controls (M=40.1±8.53 and 39.4±7.73, respectively). T-student test revealed no differences between RE and LE stimulation for N1 amplitude and latency to both groups. However, there were differences in peak-to-peak N1 amplitudes between the two groups for both LE (t=-3.067; ȡ=0.003) and RE (t=-2.794; ȡ=0.007). These findings strengthen auditory N1 has an electrophysiological biomarker for schizophrenia.
Description
Keywords
Auditory N1 - schizophrenia - Monoaural stimuli – AERPs - Biomarker
Pedagogical Context
Citation
Mota, A., Tomé, D., Campos, C. & Rocha, N. (2020). The auditory N1 in Schizophrenia: comparative analysis with a monoaural stimuli paradigm. Psychiatria Danubina, 32(2), 210-213. https://doi.org/https://doi.org/10.24869/psyd.2020.210
Publisher
Psychiatria Danubina