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Physical exercise for Parkinson’s disease: clinical and experimental evidence

dc.contributor.authorCarvalho, Alessandro Oliveira de
dc.contributor.authorFilho, Alberto Souza Sá
dc.contributor.authorMurillo-Rodriguez, Eric
dc.contributor.authorRocha, Nuno
dc.contributor.authorCarta, Mauro Giovanni
dc.contributor.authorMachado, Sérgio
dc.date.accessioned2025-01-14T10:11:13Z
dc.date.available2025-01-14T10:11:13Z
dc.date.issued2018-03-08
dc.description.abstractNational projections about the increase in the elderly population over 60 years bring with it an increase in the number of people affected by Parkinson's Disease (PD), making it an important public health problem. Therefore, the establishment of effective strategies for intervention in people with PD needs to be more clearly investigated. The study aimed to report the effectiveness of exercise on functional capacity and neurobiological mechanisms in people with PD. This study is a critical review of the literature. The progressive death of dopaminergic neurons in the substantia nigra is described as one of the main physiological mechanisms manifested before PD, directly interfering with motor behavior. However, PD is not only related to motor symptoms, but also to cognitive, autonomic, and mood impairments. Such effects may be attenuated by pharmacological influence, but also evidence suggests that the implementation of regular physical exercise programs may exhibit potential benefits over PD. The synthesis and expression of monoaminergic neurotransmitters can act positively on motor disorders, as well as directly or indirectly influence the neuronal plasticity of the brain, restoring neuronal pathways previously affected. Physical exercise contributes effectively to the treatment of PD, and can play a preventive and maintenance role of physical fitness and mental health.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationOliveira de Carvalho, A., Filho, A. S. S., Murillo-Rodriguez, E., Rocha, N. B., Carta, M. G., & Machado, S. (2018). Physical exercise for Parkinson’s disease: Clinical and experimental evidence. Clinical Practice & Epidemiology in Mental Health, 14, 89–98. https://doi.org/10.2174/1745017901814010089pt_PT
dc.identifier.doi10.2174/1745017901814010089pt_PT
dc.identifier.eissn1745-0179
dc.identifier.urihttp://hdl.handle.net/10400.22/27091
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherBentham Openpt_PT
dc.relation.publisherversionhttps://clinical-practice-and-epidemiology-in-mental-health.com/VOLUME/14/PAGE/89/pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectParkinson’s diseasept_PT
dc.subjectAerobic exercisept_PT
dc.subjectStrength trainingpt_PT
dc.subjectBrain-derived neurotrophic factorpt_PT
dc.subjectPhysical fitnesspt_PT
dc.subjectMood impairmentpt_PT
dc.titlePhysical exercise for Parkinson’s disease: clinical and experimental evidencept_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage98pt_PT
oaire.citation.startPage89pt_PT
oaire.citation.titleClinical Practice & Epidemiology in Mental Healthpt_PT
oaire.citation.volume14pt_PT
person.familyNameRocha
person.givenNameNuno
person.identifier192266
person.identifier.ciencia-idAE16-A494-5F8B
person.identifier.orcid0000-0002-3139-2786
person.identifier.ridM-9821-2013
person.identifier.scopus-author-id32867975300
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication9e940914-601a-4978-8d5b-74e5ade7ada7
relation.isAuthorOfPublication.latestForDiscovery9e940914-601a-4978-8d5b-74e5ade7ada7

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