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SMASK- Smart Mask with colorimetric biosensor for SARS-CoV-2 contamination and humidity

2022-10-07Master thesis Open access
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dc.contributor.advisorVieira, Mónica
dc.contributor.authorNascimento, Ana Margarida Duarte
dc.date.accessioned2023-01-16T15:50:22Z
dc.date.available2023-01-16T15:50:22Z
dc.date.issued2022-10-07
dc.description.abstractThe SARS-CoV-2 virus, which causes COVID-19 disease, has been a major concern these days. Much research has emerged to understand its mechanism of action, develop strategies to minimize its contagion and its potential effects. This disease has caused enormous human and economic damage, as well as significant global challenges. This project arose during the COVID-19 pandemic and sought to explore the development of a colorimetric biosensor consisting of two sensors, subsequently incorporated into a textile surface, with the ability to directly indicate the effectiveness of the protection of face masks, through a humidity indicator and an indicator of the presence of the SARS-CoV-2 virus. For the humidity sensor two alternatives were used: clay and silica; for the virus detection sensor the biomolecules ACE2 and Sialic Acid were used. According to the results obtained, for the sensor that detects humidity levels the silica-based technology proved to be the most reliable. For the biosensor that detects the presence of the virus, the binding of the NPsAu-AS was confirmed through FTIR and STEM, and therefore proved to be the best option either economically or in terms of laboratory work.pt_PT
dc.identifier.tid203160630pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.22/21562
dc.language.isoengpt_PT
dc.subjectBiosensorpt_PT
dc.subjectSARS-CoV-2 viruspt_PT
dc.subjectCOVID-19pt_PT
dc.subjectMoisturept_PT
dc.subjectFace maskpt_PT
dc.titleSMASK- Smart Mask with colorimetric biosensor for SARS-CoV-2 contamination and humiditypt_PT
dc.typemaster thesis
dspace.entity.typePublication
rcaap.rightsopenAccesspt_PT
rcaap.typemasterThesispt_PT
thesis.degree.nameBioquímica em Saúdept_PT

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