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Advisor(s)
Abstract(s)
The increase of tissue transparency
through sequential optical immersion
clearing treatments and treatment reversibility have high interest for clinical
applications. To evaluate the clearing
reversibility in a broad spectral range and
the magnitude of the transparency created by a second treatment, the present study consisted on measuring the spectral collimated transmittance of lung tissues during a sequence of two
treatments with electronic cigarette (e-cig) fluid, which was intercalated with
an immersion in saline. The saline immersion clearly reverted the clearing
effect in the lung tissue in the spectral range between 220 and 1000 nm. By a
later application of a second treatment with the e-cig fluid, the magnitude of
the optical clearing effect was observed to be about the double as the one
observed in the first treatment, showing that the molecules of the optical clearing agent might have converted some bound water into mobile water during
the first treatment.
Description
Keywords
Electronic cigarette fluid Increased tissue transparency Lung tissue Optical clearing reversibility Refractive index matching mechanism Tissue dehydration mechanism
Citation
Publisher
Wiley