Application of cryolipolysis in adipose tissue: A systematic review

Resende, Leonor; Noites, Andreia; Amorim, Manuela

Publication

Application of cryolipolysis in adipose tissue: A systematic review

2022-07-20Journal article

dc.contributor.author	Resende, Leonor
dc.contributor.author	Noites, Andreia
dc.contributor.author	Amorim, Manuela
dc.date.accessioned	2022-11-11T17:00:17Z
dc.date.available	2022-11-11T17:00:17Z
dc.date.issued	2022-07-20
dc.description.abstract	Cryolipolysis is characterized by localized and controlled cooling of the subcutaneous adipose tissue, in a non-invasive way, causing a localized panniculitis, followed by adipocyte death by apoptosis and, consequently, a decrease in adipose tissue in the treated area. To evaluate the scientific evidence and methodological qualities about effects, adverse reactions, and level of satisfaction of cryolipolysis for the reduction of sub cutaneous adipose tissue. A systematic review was carried out according to the PRISMA recommen dation. Searches were conducted in different databases. We included studies that used a randomized control and self-control design and were carried out in humans. Articles published in English and Portuguese were screened, with no time limit regard ing the year of publication. The methodological quality of the studies was assessed using the Cochrane Rob2 scale. Of 381 articles, seven were considered eligible for inclusion. After applying the Cochrane Rob2 scale, five studies were included in the final sample. Most studies showed significant results for cryolipolysis in reducing localized fat. The incorpora tion of a dietary program into the treatment was shown to contribute to a significant improvement in the lipid profile and liver enzymes, which does not happen when cry olipolysis is applied in isolation. Rare adverse effects have been identified, but never persisting beyond a month. Cryolipolysis is an effective technique for reducing localized fat, safe, and well tolerated, with most participants satisfied at the end of the treatment. However, more randomized controlled studies should be carried out, since there is a limited number of articles with good methodological quality.	pt_PT
dc.description.version	info:eu-repo/semantics/publishedVersion	pt_PT
dc.identifier.citation	Resende, L., Noites, A., & Amorim, M. (2022). Application of cryolipolysis in adipose tissue: A systematic review. Journal of Cosmetic Dermatology, 21(10), 4122-4132. https://doi.org/10.1111/jocd.15265	pt_PT
dc.identifier.doi	10.1111/jocd.15265	pt_PT
dc.identifier.eissn	1473-2165
dc.identifier.issn	1473-2130
dc.identifier.uri	http://hdl.handle.net/10400.22/21009
dc.language.iso	eng	pt_PT
dc.peerreviewed	yes	pt_PT
dc.publisher	Wiley	pt_PT
dc.relation.publisherversion	https://onlinelibrary.wiley.com/doi/full/10.1111/jocd.15265	pt_PT
dc.rights.uri	http://creativecommons.org/licenses/by-nc/4.0/	pt_PT
dc.subject	Adverse effects	pt_PT
dc.subject	Cryotherapy	pt_PT
dc.subject	Lipodystrophy	pt_PT
dc.subject	Subcutaneous fat	pt_PT
dc.subject	Systematic review	pt_PT
dc.title	Application of cryolipolysis in adipose tissue: A systematic review	pt_PT
dc.type	journal article
dspace.entity.type	Publication
oaire.citation.endPage	11	pt_PT
oaire.citation.startPage	1	pt_PT
oaire.citation.title	Journal of Cosmetic Dermatology	pt_PT
person.familyName	Noites
person.familyName	Amorim Sousa
person.givenName	Andreia
person.givenName	Maria Manuela
person.identifier.ciencia-id	4918-EB69-ED9C
person.identifier.ciencia-id	CD1D-1B47-A971
person.identifier.orcid	0000-0002-2590-962X
person.identifier.orcid	0009-0006-1887-4840
person.identifier.scopus-author-id	55749467200
rcaap.rights	closedAccess	pt_PT
rcaap.type	article	pt_PT
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relation.isAuthorOfPublication	10df22ed-9823-452e-89a8-8cbe89e717ec
relation.isAuthorOfPublication.latestForDiscovery	1cd76bec-4c53-44eb-b484-5f2d774b7fbb