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Evaluation of OCA diffusivity in tissues through diffuse reflection spectroscopy

2022Conference object Restricted access
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dc.contributor.authorMartins, Inês S.
dc.contributor.authorPinheiro, M. R.
dc.contributor.authorSilva, H. F.
dc.contributor.authorTuchin, V. V.
dc.contributor.authorOliveira, Luís M.
dc.date.accessioned2023-02-16T11:35:01Z
dc.date.embargo2035-12-31
dc.date.issued2022
dc.description.abstractThe evaluation of the diffusion properties of optical clearing agents in biological tissues, which are necessary to characterize the transparency mechanisms, has been traditionally made using ex vivo tissues. With the objective of performing such evaluation in vivo, this study was made to evaluate and compare those properties for propylene glycol in skeletal muscle, as obtained with the collimated transmittance and diffuse reflectance kinetics. The diffusion time and the diffusion coefficient of propylene glycol in the muscle that were calculated both from transmittance and reflectance kinetics presented a deviation of 0.8%, a result that opens the possibility to use such a method in vivo.pt_PT
dc.description.sponsorshipThis research was supported by the Portuguese grant FCT-UIDB/04730/2020. VVT was supported by the RF MSHE grant 13.2251.21.0009.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1109/ICLO54117.2022.9840041pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.22/22347
dc.language.isoengpt_PT
dc.publisherIEEEpt_PT
dc.relation13.2251.21.0009pt_PT
dc.relationCenter for Innovation in Industrial Engineering and Technology
dc.relation.publisherversionhttps://ieeexplore.ieee.org/document/9840041pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectTissue optical clearingpt_PT
dc.subjectTransparency mechanismspt_PT
dc.subjectCollimated transmittancept_PT
dc.subjectDiffuse reflectancept_PT
dc.subjectDiffusion timept_PT
dc.subjectDiffusion coefficient.pt_PT
dc.titleEvaluation of OCA diffusivity in tissues through diffuse reflection spectroscopypt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.awardTitleCenter for Innovation in Industrial Engineering and Technology
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04730%2F2020/PT
oaire.citation.endPage1pt_PT
oaire.citation.startPage1pt_PT
oaire.fundingStream6817 - DCRRNI ID
person.familyNameMartins
person.familyNameOliveira
person.givenNameInês
person.givenNameLuís
person.identifier414820
person.identifier.ciencia-idC312-F342-BD23
person.identifier.orcid0000-0003-2876-3686
person.identifier.orcid0000-0003-0667-3428
person.identifier.ridB-7198-2017
person.identifier.scopus-author-id55853723900
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsclosedAccesspt_PT
rcaap.typeconferenceObjectpt_PT
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relation.isAuthorOfPublication4e2de4d7-142a-400f-8dbf-cd0ff9551093
relation.isAuthorOfPublication.latestForDiscoveryb92cdee2-1e37-46f7-b392-4739075f273d
relation.isProjectOfPublicationcdbfce2f-6ff0-4d59-a7c6-96c99d52a570
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