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Optimal solution of the fractional order breast cancer competition model

dc.contributor.authorHassani, H.
dc.contributor.authorMachado, J. A. Tenreiro
dc.contributor.authorAvazzadeh, Z.
dc.contributor.authorSafari, E.
dc.contributor.authorMehrabi, S.
dc.date.accessioned2021-09-29T14:54:16Z
dc.date.available2021-09-29T14:54:16Z
dc.date.issued2021
dc.description.abstractIn this article, a fractional order breast cancer competition model (F-BCCM) under the Caputo fractional derivative is analyzed. A new set of basis functions, namely the generalized shifted Legendre polynomials, is proposed to deal with the solutions of F-BCCM. The F-BCCM describes the dynamics involving a variety of cancer factors, such as the stem, tumor and healthy cells, as well as the effects of excess estrogen and the body’s natural immune response on the cell populations. After combining the operational matrices with the Lagrange multipliers technique we obtain an optimization method for solving the F-BCCM whose convergence is investigated. Several examples show that a few number of basis functions lead to the satisfactory results. In fact, numerical experiments not only confirm the accuracy but also the practicability and computational efficiency of the devised technique.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1038/s41598-021-94875-1pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.22/18629
dc.language.isoengpt_PT
dc.publisherNaturept_PT
dc.relation.publisherversionhttps://www.nature.com/articles/s41598-021-94875-1pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectFractional order breast cancer competition modelpt_PT
dc.subjectCaputo fractional derivativept_PT
dc.subjectF-BCCMpt_PT
dc.titleOptimal solution of the fractional order breast cancer competition modelpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue1pt_PT
oaire.citation.titleScientific Reportspt_PT
oaire.citation.volume11pt_PT
person.familyNameTenreiro Machado
person.givenNameJ. A.
person.identifier.ciencia-id7A18-4935-5B29
person.identifier.orcid0000-0003-4274-4879
person.identifier.ridM-2173-2013
person.identifier.scopus-author-id55989030100
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication82cd5c17-07b6-492b-b3e3-ecebdad1254f
relation.isAuthorOfPublication.latestForDiscovery82cd5c17-07b6-492b-b3e3-ecebdad1254f

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