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Activity-dependent neurorehabilitation beyond physical trainings: "mental exercise" through mirror neuron activation

dc.contributor.authorYuan, Ti-Fei
dc.contributor.authorChen, Wei
dc.contributor.authorShan, Chunlei
dc.contributor.authorRocha, Nuno
dc.contributor.authorArias-Carrión, Oscar
dc.contributor.authorPaes, Flávia
dc.contributor.authorde Sa, Alberto Souza
dc.contributor.authorMachado, Sergio
dc.date.accessioned2016-01-08T10:34:59Z
dc.date.available2016-11-01T01:30:09Z
dc.date.issued2015
dc.description.abstractThe activity dependent brain repair mechanism has been widely adopted in many types of neurorehabilitation. The activity leads to target specific and non-specific beneficial effects in different brain regions, such as the releasing of neurotrophic factors, modulation of the cytokines and generation of new neurons in adult hood. However physical exercise program clinically are limited to some of the patients with preserved motor functions; while many patients suffered from paralysis cannot make such efforts. Here the authors proposed the employment of mirror neurons system in promoting brain rehabilitation by "observation based stimulation". Mirror neuron system has been considered as an important basis for action understanding and learning by mimicking others. During the action observation, mirror neuron system mediated the direct activation of the same group of motor neurons that are responsible for the observed action. The effect is clear, direct, specific and evolutionarily conserved. Moreover, recent evidences hinted for the beneficial effects on stroke patients after mirror neuron system activation therapy. Finally some music-relevant therapies were proposed to be related with mirror neuron system.pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.22/7333
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherBentham Science Publisherspt_PT
dc.relation.publisherversionhttp://www.ingentaconnect.com/content/ben/cnsnddt/2015/00000014/00000010/art00005pt_PT
dc.subjectMirror neuron systempt_PT
dc.subjectbrain stimulationpt_PT
dc.subjectneurorehabilitationpt_PT
dc.subjectstrokept_PT
dc.titleActivity-dependent neurorehabilitation beyond physical trainings: "mental exercise" through mirror neuron activationpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage1271pt_PT
oaire.citation.startPage1267pt_PT
oaire.citation.titleCNS and Neurological Disorders - Drug Targetspt_PT
oaire.citation.volume14pt_PT
person.familyNameRocha
person.givenNameNuno
person.identifier192266
person.identifier.ciencia-idAE16-A494-5F8B
person.identifier.orcid0000-0002-3139-2786
person.identifier.ridM-9821-2013
person.identifier.scopus-author-id32867975300
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication9e940914-601a-4978-8d5b-74e5ade7ada7
relation.isAuthorOfPublication.latestForDiscovery9e940914-601a-4978-8d5b-74e5ade7ada7

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