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Association between maternal cardiometabolic risk factors and oral health of infants

dc.contributor.authorPestana, Rebeca Saad
dc.contributor.authorBaptista, Manuel
dc.contributor.authorMagalhães, Inês
dc.contributor.authorMorais, Juliana
dc.contributor.authorFerreira, Ana Filipa
dc.contributor.authorMarques, Sofia Cameron
dc.contributor.authorJerónimo, Maria Luís
dc.contributor.authorPinto, Carla
dc.contributor.authorSousa, Marta
dc.contributor.authorFalcão-Pires, Inês
dc.contributor.authorDuister, Denise
dc.contributor.authorZaura, Egija
dc.contributor.authorAzevedo, Maria João
dc.contributor.authorMaia, Benedita Sampaio
dc.date.accessioned2025-11-12T12:40:16Z
dc.date.available2025-11-12T12:40:16Z
dc.date.issued2025-05
dc.description.abstractMaternal health conditions during pregnancy influence infant health1-3. Cardiometabolic risk factors (CRFs), such as obesity, hypertension, and gestational diabetes, increase maternal and neonatal complications due to chronic inflammation, which disrupts immune and endocrine adaptation4,5. While the effects of CRFs on infant development are well studied, their impact on oral health remains unclear. Therefore, this study aims to assess the association between maternal CRFs and oral health of infants at three years of age. The prospective OralBioBorn cohort follows pregnant women (healthy and with CRFs) and their children up to 36 months postpartum. At age three, oral hygiene habits, caries experience using ICDAS, and Quigley-Hein plaque index (PI) of children were assessed. PI was evaluated on buccal and lingual surfaces. Preliminary data from 36 children (26 from healthy mothers, 10 from mothers with CRFs) showed no cavitated, missing, or filled teeth due to caries, nor PUFA Index lesions, in either group. The PI did not differ significantly between children of healthy mothers and those of mothers with CRFs (0.17±0.32 vs. 0.49±0.72, p>0.05, Mann-Whitney U test). The lack of associations between maternal CRFs and child oral health may reflect multiple factors, including the small sample size, the young age of the children, and the possibility that maternal CRFs do not exert a strong early influence on oral health. Future work will focus on evaluating a larger cohort and considering additional determinants, such as oral hygiene and dietary habits, which may play a more prominent role in shaping early oral health outcomes. This will provide a deeper understanding of potential mediating factors influencing early oral health trajectoriespor
dc.description.sponsorshipNWA.1389.20.080
dc.identifier.citationPestana, R. S., Baptista, M., Magalhães, I., Morais, J., Ferreira, A. F., Marques, S. C., Jerónimo, M. L., Pinto, C., Sousa, M., Falcão-Pires, I., Duister, D., Zaura, E., Azevedo, M. J., & Maia, B. S. (2025). Association between maternal cardiometabolic risk factors and oral health of infants. Livro de Resumos do 18º Encontro de Investigação Jovem da U.Porto, 945–946. https://www.up.pt/ijup/wp-content/uploads/sites/892/2025/06/Livro-de-Resumos_IJUP-2025.pdf
dc.identifier.isbn978-989-746-418-8
dc.identifier.urihttp://hdl.handle.net/10400.22/30845
dc.language.isoeng
dc.peerreviewedyes
dc.publisherUniversidade do Porto
dc.relation.hasversionhttps://www.up.pt/ijup/wp-content/uploads/sites/892/2025/06/Livro-de-Resumos_IJUP-2025.pdf
dc.rights.uriN/A
dc.subjectMaternal cardiometabolic risk factor
dc.subjectObesity
dc.subjectHypertension
dc.subjectGestational diabetes
dc.subjectChildren's oral health
dc.titleAssociation between maternal cardiometabolic risk factors and oral health of infantspor
dc.typeconference poster
dspace.entity.typePublication
oaire.citation.conferenceDate2025-05
oaire.citation.conferencePlacePorto
oaire.citation.endPage946
oaire.citation.startPage945
oaire.citation.titleLivro de Resumos do 18º Encontro de Investigação Jovem da U.Porto
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85

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