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Speech- and Language-Based Classification of Alzheimer’s Disease: A Systematic Review

dc.contributor.authorVigo, Inês
dc.contributor.authorCoelho, Luis
dc.contributor.authorReis, Sara Seabra dos
dc.date.accessioned2023-01-18T11:08:39Z
dc.date.available2023-01-18T11:08:39Z
dc.date.issued2022
dc.description.abstractBackground: Alzheimer’s disease (AD) has paramount importance due to its rising prevalence, the impact on the patient and society, and the related healthcare costs. However, current diagnostic techniques are not designed for frequent mass screening, delaying therapeutic intervention and worsening prognoses. To be able to detect AD at an early stage, ideally at a pre-clinical stage, speech analysis emerges as a simple low-cost non-invasive procedure. Objectives: In this work it is our objective to do a systematic review about speech-based detection and classification of Alzheimer’s Disease with the purpose of identifying the most effective algorithms and best practices. Methods: A systematic literature search was performed from Jan 2015 up to May 2020 using ScienceDirect, PubMed and DBLP. Articles were screened by title, abstract and full text as needed. A manual complementary search among the references of the included papers was also performed. Inclusion criteria and search strategies were defined a priori. Results: We were able: to identify the main resources that can support the development of decision support systems for AD, to list speech features that are correlated with the linguistic and acoustic footprint of the disease, to recognize the data models that can provide robust results and to observe the performance indicators that were reported. Discussion: A computational system with the adequate elements combination, based on the identified best-practices, can point to a whole new diagnostic approach, leading to better insights about AD symptoms and its disease patterns, creating conditions to promote a longer life span as well as an improvement in patient quality of life. The clinically relevant results that were identified can be used to establish a reference system and help to define research guidelines for future developments.pt_PT
dc.description.sponsorshipThis work was partially supported by FCT- UIDB/04730/2020 project.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.3390/bioengineering9010027pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.22/21631
dc.language.isoengpt_PT
dc.publisherMDPIpt_PT
dc.relationCenter for Innovation in Industrial Engineering and Technology
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectAlzheimer’s disease (AD)pt_PT
dc.subjectSpeechpt_PT
dc.subjectClassificationpt_PT
dc.subjectFeaturespt_PT
dc.subjectMachine learning (ML)pt_PT
dc.subjectMild cognitive impairment (MCI)pt_PT
dc.titleSpeech- and Language-Based Classification of Alzheimer’s Disease: A Systematic Reviewpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleCenter for Innovation in Industrial Engineering and Technology
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04730%2F2020/PT
oaire.citation.issue1pt_PT
oaire.citation.startPage27pt_PT
oaire.citation.titleBioengineeringpt_PT
oaire.citation.volume9pt_PT
oaire.fundingStream6817 - DCRRNI ID
person.familyNameCoelho
person.familyNameSeabra dos Reis
person.givenNameLuis
person.givenNameSara
person.identifier721155
person.identifier.ciencia-id9B14-241F-3743
person.identifier.ciencia-idF41A-6E80-8361
person.identifier.orcid0000-0002-5673-7306
person.identifier.orcid0000-0002-3416-2257
person.identifier.ridC-9695-2015
person.identifier.scopus-author-id55027243400
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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relation.isAuthorOfPublication27493a08-3eb7-4d61-be68-770bf5fa00e3
relation.isAuthorOfPublication.latestForDiscovery27493a08-3eb7-4d61-be68-770bf5fa00e3
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