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Exercise induced neuroplasticity to enhance therapeutic outcomes of cognitive remediation in schizophrenia: Analyzing the role of brain-derived neurotrophic factor

2017-07-31Journal article Open access
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dc.contributor.authorCampos, C.
dc.contributor.authorRocha, Nuno
dc.contributor.authorLattari, Eduardo
dc.contributor.authorNardi, António E.
dc.contributor.authorMachado, Sérgio
dc.date.accessioned2021-12-07T11:40:55Z
dc.date.available2021-12-07T11:40:55Z
dc.date.issued2017-07-31
dc.description.abstractCognitive impairment is a major manifestation of schizophrenia and a crucial treatment target as these deficits are closely related to patients' functional outcomes. Cognitive remediation is the gold-standard practice to address cognitive deficits in schizophrenia. There is clear evidence stating that cognitive remediation improves cognitive function and promotes structural neuroplastic changes in patients with schizophrenia, with brain-derived neurotrophic factor (BDNF) expression emerging as a potential biomarker for its efficacy. This is particularly important as there is clear evidence relating atypical BDNF expression to cognitive impairment in patients with schizophrenia. Despite the valuable role of cognitive remediation in the management of schizophrenia, there is still a need to develop methods that allow maximizing its efficacy.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationCampos, C., Rocha, N. B., Lattari, E., Nardi, A. E., & Machado, S. (2017). Exercise Induced Neuroplasticity to Enhance Therapeutic Outcomes of Cognitive Remediation in Schizophrenia: Analyzing the Role of Brain derived Neurotrophic Factor. CNS & Neurological Disorders Drug Targets, 16 6, 638-651.pt_PT
dc.identifier.doi10.2174/1871527315666161223142918pt_PT
dc.identifier.eissn1996-3181
dc.identifier.urihttp://hdl.handle.net/10400.22/19012
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherBentham Sciencept_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectBrain-derived neurotrophic factorpt_PT
dc.subjectCognitive remediationpt_PT
dc.subjectExercisept_PT
dc.subjectLearningpt_PT
dc.subjectNeuroplasticitypt_PT
dc.subjectSchizophreniapt_PT
dc.titleExercise induced neuroplasticity to enhance therapeutic outcomes of cognitive remediation in schizophrenia: Analyzing the role of brain-derived neurotrophic factorpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage651pt_PT
oaire.citation.startPage638pt_PT
oaire.citation.titleCNS & Neurological Disorders - Drug Targetspt_PT
oaire.citation.volume16pt_PT
person.familyNameCampos
person.familyNameRocha
person.givenNameCarlos
person.givenNameNuno
person.identifier192266
person.identifier.ciencia-idB518-6A52-D50F
person.identifier.ciencia-idAE16-A494-5F8B
person.identifier.orcid0000-0002-5966-4050
person.identifier.orcid0000-0002-3139-2786
person.identifier.ridM-9821-2013
person.identifier.scopus-author-id56567519500
person.identifier.scopus-author-id32867975300
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationf9744770-c154-483e-b271-b58d1089d55f
relation.isAuthorOfPublication9e940914-601a-4978-8d5b-74e5ade7ada7
relation.isAuthorOfPublication.latestForDiscovery9e940914-601a-4978-8d5b-74e5ade7ada7

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