Publication
Understanding methodologies applied to Giardia lamblia and Trichomonas vaginalis: from isolation to in vitro screening
| dc.contributor.advisor | Cruz, Agostinho Luís da Silva | |
| dc.contributor.author | Sequeira, Susie Gonçalves | |
| dc.date.accessioned | 2025-02-20T11:46:39Z | |
| dc.date.available | 2025-02-20T11:46:39Z | |
| dc.date.issued | 2024-11-20 | |
| dc.date.submitted | 2024-11-20 | |
| dc.description.abstract | Protozoan parasitic infections continue to represent a public health problema, with giardiasis, an intestinal parasitoses, and trichomonas, a sexually transmitted disease, being particularly noteworthy. Metronidazole remains the gold standard for treating both parasitic diseases.however the increasing number of record resistance cases and the side effects of these drug highlight the need to discover new compounds with therapeutic potential. Medicinal plants constitute a valuable source of new therapeutic compounds due to the diverse biological activities of their phytochemical constituents. The main objective of this study was to evaluate the antiparasitic potential of selected medicinal plants on trophozoites of Giardia lamblia and Trichomonas vaginalis. To achieve this goal, two systematic reviews were conducted, employing the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA 2020) methodology, on techniques used throughout the life cycle of G. lamblia and viability assays used to evaluate the antigiardial and antitrichomonal activity of compounds with therapeutic potential. Furthermore, experimental assays were conducted to determine the antiparasitic potential of aqueous and methanolic extracts of medicinal plants selected based on ethnobotanical studies carried out in Portugal. | por |
| dc.identifier.tid | 203868722 | |
| dc.identifier.uri | http://hdl.handle.net/10400.22/29613 | |
| dc.language.iso | eng | |
| dc.rights.uri | N/A | |
| dc.subject | Ethnobotany | |
| dc.subject | Giardia lamblia | |
| dc.subject | In vitro screening | |
| dc.subject | Medicinal plants | |
| dc.subject | Trichomonas vaginalis | |
| dc.title | Understanding methodologies applied to Giardia lamblia and Trichomonas vaginalis: from isolation to in vitro screening | por |
| dc.type | master thesis | |
| dspace.entity.type | Publication |