Publication
Central and peripheral involvement of the retina in the initial stages of diabetic retinophaty
| dc.contributor.author | Santos, Ana Rita | |
| dc.contributor.author | Almeida, Ana Catarina | |
| dc.contributor.author | Rocha, Ana Cláudia | |
| dc.contributor.author | Reste-Ferreira, Débora | |
| dc.contributor.author | Marques, Inês Pereira | |
| dc.contributor.author | Martinho, António Cunha-Vaz | |
| dc.contributor.author | Mendes, Luís | |
| dc.contributor.author | Santos, Torcato | |
| dc.contributor.author | Lewis, Warren | |
| dc.contributor.author | Cunha-Vaz, José | |
| dc.contributor.author | Santos, Ana Rita | |
| dc.date.accessioned | 2025-06-20T08:37:39Z | |
| dc.date.available | 2025-06-20T08:37:39Z | |
| dc.date.issued | 2024-04 | |
| dc.description.abstract | To determine the degree of central microvascular closure using optical coherence tomography angiography in eyes of patients with type 2 diabetes with visible lesions only in the central retina or only in the periphery. Cross-sectional study. All 127 eyes underwent ultra-widefield fundus photography 200° examinations with OPTOS California (Optos, Dunfermline, United Kingdom) and Cirrus Angioplex optical coherence tomography angiography 3 × 3 mm acquisitions (ZEISS, Dublin, CA). Twenty-five eyes showed visible lesions only in the central retina, 57 only in the peripheral retina, and 45 presented visible lesions in entire retina. The group with visible lesions only in the periphery showed definite closure in the superficial capillary plexus in 49% of the eyes, whereas the group with visible lesions only in the central seven-early treatment diabetic retinopathy study fields area showed a definite closure in 64%. Central capillary closure is already present in the initial stages of diabetic retinopathy even when lesions are only visible in the peripheral retina. Capillary closure in the superficial capillary plexus is three times more frequent than in the deep capillary plexus, demonstrating earlier closure of the superficial capillary plexus. Eyes with visible lesions only in the periphery show a milder form of retinopathy. | por |
| dc.identifier.citation | Santos, A. R., Almeida, A. C., Rocha, A. C., Reste-Ferreira, D., Marques, I. P., Cunha-Vaz Martinho, A., Mendes, L., Santos, T., Lewis, W., & Cunha-Vaz, J. (2024). Central and peripheral involvement of the retina in the initial stages of diabetic retinophaty. RETINA, 44(4), 700. https://doi.org/10.1097/IAE.0000000000004021 | |
| dc.identifier.eissn | 1539-2864 | |
| dc.identifier.issn | 0275-004X | |
| dc.identifier.uri | http://hdl.handle.net/10400.22/30165 | |
| dc.language.iso | eng | |
| dc.peerreviewed | yes | |
| dc.publisher | Wolters Klumer | |
| dc.relation.hasversion | https://journals.lww.com/retinajournal/fulltext/2024/04000/central_and_peripheral_involvement_of_the_retina.18.aspx | |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
| dc.subject | Diabetic retinopathy | |
| dc.subject | Peripheral retina | |
| dc.subject | Ultra-widefield imaging | |
| dc.subject | Color fundus photography | |
| dc.subject | OCTA | |
| dc.subject | Skeletonized vessel density | |
| dc.title | Central and peripheral involvement of the retina in the initial stages of diabetic retinophaty | por |
| dc.type | research article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 706 | |
| oaire.citation.issue | 4 | |
| oaire.citation.startPage | 700 | |
| oaire.citation.title | RETINA - The Journal of Retinal and Vitreus Diseases | |
| oaire.citation.volume | 44 | |
| oaire.version | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |
| person.familyName | Santos | |
| person.givenName | Ana Rita | |
| person.identifier.ciencia-id | 0911-4138-0C3A | |
| person.identifier.orcid | 0000-0003-0139-0285 | |
| relation.isAuthorOfPublication | d71931b8-d869-4334-993c-ba14ad713f01 | |
| relation.isAuthorOfPublication.latestForDiscovery | d71931b8-d869-4334-993c-ba14ad713f01 |