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Monitoring adherence to asthma inhalers using the InspirerMundi App: Analysis of real-world, Medium-term feasibility studies

dc.contributor.authorJàcome, Cristina
dc.contributor.authorAmaral, Rita
dc.contributor.authorAmaral, Rita
dc.date.accessioned2025-06-03T08:03:16Z
dc.date.available2025-06-03T08:03:16Z
dc.date.issued2021-07-15
dc.description.abstract"Poor medication adherence is a major challenge in asthma and objective assessment of inhaler adherence is needed. InspirerMundi app aims to monitor inhaler adherence while turning it into a positive experience through gamification and social support. We assessed the medium-term feasibility of the InspirerMundi app to monitor inhaler adherence in real-world patients with persistent asthma (treated with daily inhaled medication). In addition, we attempted to identify the characteristics of the patients related to higher app use. Two real-world multicenter observational studies, with one initial face-to-face visit and a 4-month telephone interview, were conducted in 29 secondary care centers from Portugal. During an initial face-to-face visit, patients were invited to use the app daily to register their asthma medication intakes. A scheduled intake was considered taken when patients took a photo of the medication (inhaler, blister, or others) using the image-based medication detection tool. Medication adherence was calculated as the number of doses taken as a percentage of the number scheduled. Interacting with the app ≥30 days was used as the cut-off for higher app use. A total of 114 patients {median 20 [percentile 25 to percentile 75 (P25–P75) 16–36] years, 62% adults} were invited, 107 (94%) installed the app and 83 (73%) completed the 4-month interview. Patients interacted with the app for a median of 18 [3–45] days, translated on a median use rate of 15 [3–38]%. Median inhaler adherence assessed through the app was 34 [4–73]% when considering all scheduled inhalations for the study period. Inhaler adherence assessed was not significantly correlated with self-reported estimates. Median adherence for oral and other medication was 41 [6–83]% and 43 [3–73]%, respectively. Patients with higher app use were slightly older (p = 0.012), more frequently taking medication for other health conditions (p = 0.040), and more frequently prescribed long-acting muscarinic antagonists (LAMA, p = 0.024). After 4 months, Control of Allergic Rhinitis and Asthma Test (CARAT) scores improved (p < 0.001), but no differences between patients interacting with the app for 30 days or less were seen. The InspirerMundi app was feasible to monitor inhaler adherence in patients with persistent asthma. The persistent use of this mHealth technology varies widely. A better understanding of characteristics related to higher app use is still needed before effectiveness studies are undertaken. "por
dc.identifier.citationJácome, C., Almeida, R., Pereira, A. M., Amaral, R., Vieira-Marques, P., Mendes, S., Alves-Correia, M., Ferreira, J. A., Lopes, I., Gomes, J., Araújo, L., Couto, M., Chaves Loureiro, C., Santos, L. M., Arrobas, A., Valério, M., Todo Bom, A., Azevedo, J., Teixeira, M. F., … Fonseca, J. A. (2021). Monitoring adherence to asthma inhalers using the InspirerMundi App: Analysis of real-world, medium-term feasibility studies. Frontiers in Medical Technology, 3. https://doi.org/10.3389/fmedt.2021.649506
dc.identifier.doi10.3389/fmedt.2021.649506
dc.identifier.eissn2673-3129
dc.identifier.urihttp://hdl.handle.net/10400.22/30132
dc.language.isoeng
dc.peerreviewedyes
dc.publisherFrontiers
dc.relationPOCI-01-0145-36 FEDER- 029130
dc.relation.hasversionhttps://www.frontiersin.org/journals/medical-technology/articles/10.3389/fmedt.2021.649506/full
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectmHealth
dc.subjectSmartphone
dc.subjectTechnology assessment
dc.subjectMedication adherence
dc.subjectSelf-management
dc.subjectPatient participation
dc.titleMonitoring adherence to asthma inhalers using the InspirerMundi App: Analysis of real-world, Medium-term feasibility studiespor
dc.typeresearch article
dspace.entity.typePublication
oaire.citation.issueArticle 649506
oaire.citation.titleFrontiers in Medical Technology
oaire.citation.volume3
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameAmaral
person.givenNameRita
person.identifierR-00H-83K
person.identifier.ciencia-id1A1E-751F-50F0
person.identifier.orcid0000-0002-0233-830X
person.identifier.ridE-5535-2017
person.identifier.scopus-author-id56067841600
relation.isAuthorOfPublication790fdd33-acdb-4dfe-88dc-38538486c9b3
relation.isAuthorOfPublication.latestForDiscovery790fdd33-acdb-4dfe-88dc-38538486c9b3

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