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Hydroxycinnamic acid antioxidants: an electrochemical overview

dc.contributor.authorTeixeira, José
dc.contributor.authorGaspar, Alexandra
dc.contributor.authorGarrido, E. Manuela
dc.contributor.authorGarrido, Jorge
dc.contributor.authorBorges, Fernanda
dc.date.accessioned2014-01-30T15:02:56Z
dc.date.available2014-01-30T15:02:56Z
dc.date.issued2013
dc.description.abstractHydroxycinnamic acids (such as ferulic, caffeic, sinapic, and p-coumaric acids) are a group of compounds highly abundant in food that may account for about one-third of the phenolic compounds in our diet. Hydroxycinnamic acids have gained an increasing interest in health because they are known to be potent antioxidants. These compounds have been described as chain-breaking antioxidants acting through radical scavenging activity, that is related to their hydrogen or electron donating capacity and to the ability to delocalize/stabilize the resulting phenoxyl radical within their structure.The free radical scavenger ability of antioxidants can be predicted from standard one-electron potentials. Thus, voltammetric methods have often been applied to characterize a diversity of natural and synthetic antioxidants essentially to get an insight into their mechanism and also as an important tool for the rational design of new and potent antioxidants.The structure-property-activity relationships (SPARs) correlations already established for this type of compounds suggest that redox potentials could be considered a good measure of antioxidant activity and an accurate guideline on the drug discovery and development process. Due to its magnitude in the antioxidant field, the electrochemistry of hydroxycinnamic acid-based antioxidants is reviewed highlighting the structure-property-activity relationships (SPARs) obtained so far.por
dc.identifier.doi10.1155/2013/251754pt_PT
dc.identifier.issn2314-6141
dc.identifier.urihttp://hdl.handle.net/10400.22/3527
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherHindawi Publishing Corporationpor
dc.relation.ispartofseriesBioMed Research International; Vol. 2013
dc.relation.publisherversionhttp://www.hindawi.com/journals/bmri/2013/251754/por
dc.subjectHydroxycinnamic acidpor
dc.subjectAntioxidantspor
dc.subjectElectrochemistrypor
dc.titleHydroxycinnamic acid antioxidants: an electrochemical overviewpor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage11por
oaire.citation.startPage1por
oaire.citation.titleBioMed Research Internationalpor
oaire.citation.volumeVol. 2013por
person.familyNameGarrido
person.givenNameJorge
person.identifier.orcid0000-0001-8981-231X
person.identifier.scopus-author-id7202779733
rcaap.rightsopenAccesspor
rcaap.typearticlepor
relation.isAuthorOfPublicationf548e711-c68e-4c49-9471-9923c047116d
relation.isAuthorOfPublication.latestForDiscoveryf548e711-c68e-4c49-9471-9923c047116d

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