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Advisor(s)
Abstract(s)
Hydroxycinnamic acids (such as ferulic, caffeic, sinapic, and p-coumaric acids) are a group of compounds highly abundant in food
that may account for about one-third of the phenolic compounds in our diet. Hydroxycinnamic acids have gained an increasing
interest in health because they are known to be potent antioxidants. These compounds have been described as chain-breaking
antioxidants acting through radical scavenging activity, that is related to their hydrogen or electron donating capacity and to the
ability to delocalize/stabilize the resulting phenoxyl radical within their structure.The free radical scavenger ability of antioxidants
can be predicted from standard one-electron potentials. Thus, voltammetric methods have often been applied to characterize a
diversity of natural and synthetic antioxidants essentially to get an insight into their mechanism and also as an important tool
for the rational design of new and potent antioxidants.The structure-property-activity relationships (SPARs) correlations already
established for this type of compounds suggest that redox potentials could be considered a good measure of antioxidant activity
and an accurate guideline on the drug discovery and development process. Due to its magnitude in the antioxidant field, the
electrochemistry of hydroxycinnamic acid-based antioxidants is reviewed highlighting the structure-property-activity relationships
(SPARs) obtained so far.
Description
Keywords
Hydroxycinnamic acid Antioxidants Electrochemistry
Citation
Publisher
Hindawi Publishing Corporation