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Orientador(es)
Resumo(s)
It is widely known that a number of chronic neurodegenerative disorders
are related with dysfunctional mitochondria. Although it has been proposed that
Acetyl-L-Carnitine (ALC) confers neuroprotection through mitochondria viability
improvement, little is known concerning the molecular mechanisms involved. We
propose to characterize the action of ALC in mitochondria bioenergetics and functional
integrity.