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Fast calculation of spectral optical properties and pigment content detection in human normal and pathological kidney

2023-02-05Journal article Open access
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dc.contributor.authorBotelho, Ana R.
dc.contributor.authorSilva, Hugo F.
dc.contributor.authorMartins, Inês S.
dc.contributor.authorCarneiro, Isa
dc.contributor.authorCarvalho, Sónia D.
dc.contributor.authorHenrique, Rui M.
dc.contributor.authorTuchin, Valery V.
dc.contributor.authorOliveira, Luís M.
dc.date.accessioned2023-03-17T17:27:29Z
dc.date.available2023-03-17T17:27:29Z
dc.date.issued2023-02-05
dc.description.abstractA fast calculation method was used to obtain the spectral optical properties of human normal and pathological (chromophobe renal cell carcinoma) kidney tissues. Using total transmittance, total reflectance and collimated transmittance spectra acquired from ex vivo kidney samples, the spectral optical properties of both tissues, namely the absorption, the scattering and the reduced scattering coefficients, as well as the scattering anisotropy, dispersion and light penetration depth, were calculated between 200 and 1000 nm. Analysis of the mean ab sorption coefficient spectra of the kidney tissues showed that both contain melanin and lipofuscin, and that 83 % of the melanin in the normal kidney converts into lipofuscin in the pathological kidney.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationBotelho, A. R., Silva, H. F., Martins, I. S., Carneiro, I. C., Carvalho, S. D., Henrique, R. M., Tuchin, V. V., & Oliveira, L. M. (2023). Fast calculation of spectral optical properties and pigment content detection in human normal and pathological kidney. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 286, 122002. https://doi.org/10.1016/j.saa.2022.122002pt_PT
dc.identifier.doi10.1016/j.saa.2022.122002pt_PT
dc.identifier.eissn1873-3557
dc.identifier.issn1386-1425
dc.identifier.urihttp://hdl.handle.net/10400.22/22542
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relation.publisherversionhttps://www.sciencedirect.com/science/article/pii/S1386142522011507?via%3Dihubpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectHuman kidneypt_PT
dc.subjectChromophobe renal cell carcinomapt_PT
dc.subjectSpectral absorption coefficientpt_PT
dc.subjectMelaninpt_PT
dc.subjectLipofuscinpt_PT
dc.subjectRenal cancer discriminationpt_PT
dc.titleFast calculation of spectral optical properties and pigment content detection in human normal and pathological kidneypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage7pt_PT
oaire.citation.startPage1pt_PT
oaire.citation.titleSpectrochimica Acta Part A: Molecular and Biomolecular Spectroscopypt_PT
oaire.citation.volume286pt_PT
person.familyNameCarneiro
person.givenNameIsa
person.identifier.orcid0000-0002-0561-3880
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication840cfc60-06fe-434e-9cae-d01d37ab1f5b
relation.isAuthorOfPublication.latestForDiscovery840cfc60-06fe-434e-9cae-d01d37ab1f5b

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