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Predictors of acute kidney injury associated with cardiopulmonary bypass

dc.contributor.authorMoreira, Raquel
dc.contributor.authorJacinto, Tiago
dc.contributor.authorNeves, Paulo
dc.contributor.authorVouga, Luís
dc.contributor.authorBaeta, Cristina
dc.date.accessioned2023-03-28T17:01:33Z
dc.date.available2023-03-28T17:01:33Z
dc.date.issued2021-05-26
dc.description.abstractTo study the incidence of acute kidney injury (AKI) in the postoperative period of cardiac surgery in patients without preoperative renal insufficiency who underwent cardiac surgery with cardiopulmonary bypass (CPB), and to explore the association between the incidence of AKI and predictors related to CPB. Observational, cross-sectional study. Participants were divided in two groups, those who developed AKI in the postoperative period and those who did not develop AKI. Kidney Disease: Improving Global Outcomes - Clinical Practice Guideline for Acute Kidney Injury (KDIGO) classification was used to characterize AKI. The analysis included preoperative variables (anthropometric data, cardiovascular risk factors and blood parameters), as well as the type of surgery, intraoperative variables related to CPB, and postoperative creatinine variation. Association between variables was studied with binary logistic regression. We have included 329 patients, of which 62 (19%), developed AKI. There were statistically significant differences between the groups in age (p<0.001; OR (95%)-1.075 (1.037-1.114)), duration of CPB (p=0.011; 1.008 (1.002-1.014)), urine output during CPB (p=0.038; 0.998 (0.996-0.999)), mannitol and furosemide administration during CPB, (respectively, p=0.032; 2.293 (1.075-4.890) and p=0.013; 2.535 (1.214-5.296)). A significant number of patients developed AKI in the postoperative period of cardiac surgery and this incidence was influenced by factors related to CPB, namely: age, duration of CPB, urine output during CPB, mannitol and furosemide administration during CPB.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationMoreira, R., Jacinto, T., Neves, P., Vouga, L., & Baeta, C. (2021). Predictors of acute kidney injury associated with cardiopulmonary bypass. Portuguese Journal of Cardiac Thoracic and Vascular Surgery, 26(2), 109–115. https://doi.org/10.48729/pjctvs.123pt_PT
dc.identifier.doi10.48729/pjctvs.123pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.22/22614
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherSPCCTVpt_PT
dc.relation.publisherversionhttps://pjctvs.com/index.php/journal/article/view/123pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.titlePredictors of acute kidney injury associated with cardiopulmonary bypasspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage115pt_PT
oaire.citation.startPage109pt_PT
oaire.citation.titlePortuguese Journal of Cardiac Thoracic and Vascular Surgerypt_PT
oaire.citation.volume26(2)pt_PT
person.familyNameBaeta
person.givenNameCristina
person.identifier.ciencia-idED1E-5481-48E1
person.identifier.orcid0000-0002-7897-1101
person.identifier.orcid0000-0003-4112-6462
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationd8696cf3-a961-4d88-963a-cefd61572ae3
relation.isAuthorOfPublication66c6e7f2-6670-4734-97c6-bd6cd1a1724e
relation.isAuthorOfPublication.latestForDiscovery66c6e7f2-6670-4734-97c6-bd6cd1a1724e

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