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Using artificial intelligence to prioritize pathology samples: report of a test drive

dc.contributor.authorRienda, Iván
dc.contributor.authorVale, João
dc.contributor.authorPinto, João
dc.contributor.authorPolónia, António
dc.contributor.authorEloy, Catarina
dc.date.accessioned2026-01-15T14:22:55Z
dc.date.available2026-01-15T14:22:55Z
dc.date.issued2025
dc.description.abstractThe digital transformation of pathology, through automation and computational tools, addresses current challenges in the field. This study evaluates Paige Pan Cancer, a novel artificial intelligence tool based on the Virchow foundation model, designed to flag invasive cancer in haematoxylin and eosin-stained slides from 16 primary tissue types. Using 62 cases from the Ipatimup Pathology Laboratory, we found the tool had a sensitivity of 93.3% and specificity of 87.5% in biopsies, and 94.7% sensitivity and 75.0% specificity in resections. Overall accuracy was 90.3%. Despite some misclassifications, Paige Pan Cancer demonstrates high sensitivity as a multi-organ screening tool in clinical practice.eng
dc.identifier.citationRienda, I., Vale, J., Pinto, J., Polónia, A., & Eloy, C. (2025). Using artificial intelligence to prioritize pathology samples: Report of a test drive. Virchows Archiv, 487(1), 203–208. https://doi.org/10.1007/s00428-024-03988-1
dc.identifier.doi10.1007/s00428-024-03988-1
dc.identifier.eissn1432-2307
dc.identifier.issn0945-6317
dc.identifier.urihttp://hdl.handle.net/10400.22/31532
dc.language.isoeng
dc.peerreviewedyes
dc.publisherSpringer Nature
dc.relation.hasversionhttps://link.springer.com/article/10.1007/s00428-024-03988-1
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectComputational pathology
dc.subjectCancer diagnosis
dc.subjectArtificial intelligence
dc.subjectWorkflow
dc.subjectEfficiency
dc.subjectFoundation model
dc.titleUsing artificial intelligence to prioritize pathology samples: report of a test driveeng
dc.typeother type of report
dspace.entity.typePublication
oaire.citation.endPage208
oaire.citation.startPage203
oaire.citation.titleVirchows Archiv
oaire.citation.volume487
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85

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