Publication
Fast screening procedure for antibiotics in wastewaters by direct HPLC-DAD analysis
| dc.contributor.author | Teixeira, Salomé | |
| dc.contributor.author | Delerue-Matos, Cristina | |
| dc.contributor.author | Alves, Arminda | |
| dc.contributor.author | Santos, Lúcia | |
| dc.date.accessioned | 2013-11-21T15:28:51Z | |
| dc.date.available | 2013-11-21T15:28:51Z | |
| dc.date.issued | 2008 | |
| dc.description.abstract | Growing concern about the contamination of wastewaters by antibiotics demands fast but sensitive analytical methodologies, for the screening of a large number of samples. The purpose of this work was to develop a simple methodology, using direct injection of the samples, by HPLC with diode array detection (DAD), for a multiresidue analysis of five antibiotics of different classes. Wastewater from an urban water treatment plant was selected as a model to study possible coelution of interfering compounds. The linearity interval ranged from 40 to 400 µg/L for amoxicillin (Amox), metronidazole (Metro), cefazolin (Cefa), and chloramphenicol (Chloram) and from 20 to 200 µg/L for sulfamethoxazole (Sulfa), with LODs lower than 14 µg/L. Repeatability, expressed by the CV of six repeated injections, ranged from 1 to 8%, while the intermediate precision varied between 2 and 11%. The recovery ranged from 90 to 109%. This method enables the fast screening of a large number of samples, with an expanded uncertainty in the 1–22% range. The advantage of the proposed method is to significantly reduce the number of samples to be analyzed by more complex methods. | por |
| dc.identifier.doi | 10.1002/jssc.200800229 | pt_PT |
| dc.identifier.uri | http://recipp.ipp.pt/handle/10400.22/2896 | |
| dc.language.iso | eng | por |
| dc.peerreviewed | yes | por |
| dc.publisher | WILEY-VCH Verlag GmbH & Co. | por |
| dc.relation.publisherversion | https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/jssc.200800229 | por |
| dc.subject | Antibiotics | por |
| dc.subject | HPLC-DAD | por |
| dc.subject | Screening | por |
| dc.subject | Uncertainty | por |
| dc.subject | Wastewater | por |
| dc.title | Fast screening procedure for antibiotics in wastewaters by direct HPLC-DAD analysis | por |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 2931 | por |
| oaire.citation.issue | 31 | por |
| oaire.citation.startPage | 2924 | por |
| oaire.citation.title | Jss-Journal | por |
| person.familyName | Delerue-Matos | |
| person.givenName | Cristina | |
| person.identifier.ciencia-id | 9A1A-43FB-5C27 | |
| person.identifier.orcid | 0000-0002-3924-776X | |
| person.identifier.rid | D-4990-2013 | |
| person.identifier.scopus-author-id | 6603741848 | |
| rcaap.rights | openAccess | por |
| rcaap.type | article | por |
| relation.isAuthorOfPublication | 09f6a7bd-2f15-42b0-adc5-04bd22210519 | |
| relation.isAuthorOfPublication.latestForDiscovery | 09f6a7bd-2f15-42b0-adc5-04bd22210519 |