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Allergic Rhinitis and its Impact on Asthma (ARIA) Classes in MASK-air users

dc.contributor.authorBousquet, Jean
dc.contributor.authorAmaral, Rita
dc.contributor.authorAmaral, Rita
dc.date.accessioned2026-06-29T09:21:13Z
dc.date.available2026-06-29T09:21:13Z
dc.date.issued2025
dc.description.abstractThe Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines classify rhinitis as "intermittent" or "persistent" and "mild" or "moderate-severe". To assess ARIA classes in a real-world study in terms of phenotypic differences and their association with asthma. We performed a cross-sectional real-world study based on users of the MASK-air® app who reported data for at least 3 different months. We assessed the frequency of users according to the ARIA classes and compared these classes in terms of rhinitis symptoms, use of comedication, frequency of comorbid asthma, and the association between comorbid asthma and rhinitis control. A total of 2273 users (180 796 days) were assessed. Most users had moderate-severe rhinitis (n=2003; 88.1%) and persistent rhinitis (n=1144; 50.3%). The frequency of patients with probable asthma was 35.7% (95%CI, 34.5%-37.0%) for intermittent rhinitis and 48.5% (95%CI, 47.1%-49.9%) for persistent rhinitis. The maximum values on the visual analog scale (VAS) for rhinitis symptoms and the combined symptom-medication score were lower in patients with mild rhinitis than in those with moderate-severe rhinitis (irrespective of whether they had persistent or intermittent rhinitis). In most ARIA classes, VAS nose and VAS eye and rhinitis comedication were more frequent in patients with rhinitis+asthma than in those with rhinitis alone. This study suggests that the presence of asthma is more closely related to persistence of rhinitis than to severity and that the presence of comorbid asthma may be associated with poorer control of rhinitis across the different ARIA classes.eng
dc.identifier.citationSousa-Pinto, B., Savouré, M., Vieira, R., Amaral, R., Czarlewski, W., Bedbrook, A., Valiulis, A., Kvedariene, V., Brussino, L., Gemicioglu, B., Haahtela, T., Klimek, L., Kraxner, H., Larenas-Linnemann, D., Pfaar, O., Regateiro, F., Samolinski, B., Taborda-Barata, L., Toppila-Salmi, S., … Bousquet, J. (2025). Allergic Rhinitis and its Impact on Asthma (ARIA) Classes in MASK-air Users. Journal of Investigational Allergology and Clinical Immunology, 35(5), 373–383. https://doi.org/10.18176/jiaci.1047
dc.identifier.doi10.18176/jiaci.1047
dc.identifier.eissn1698-0808
dc.identifier.issn1018-9068
dc.identifier.urihttp://hdl.handle.net/10400.22/32515
dc.language.isoeng
dc.peerreviewedyes
dc.publisherSpanish Society of Allergology and Clinical Immunology (SEAIC)
dc.relation.hasversionhttps://www.jiaci.org/summary/vol35-issue5-num3126
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/
dc.subjectAllergic rhinitis
dc.subjectAsthma
dc.subjectmHealth
dc.titleAllergic Rhinitis and its Impact on Asthma (ARIA) Classes in MASK-air userseng
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage383
oaire.citation.issue5
oaire.citation.startPage373
oaire.citation.titleJournal of Investigational Allergology and Clinical Immunology
oaire.citation.volume35
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameAmaral
person.givenNameRita
person.identifierR-00H-83K
person.identifier.ciencia-id1A1E-751F-50F0
person.identifier.orcid0000-0002-0233-830X
person.identifier.ridE-5535-2017
person.identifier.scopus-author-id56067841600
relation.isAuthorOfPublication790fdd33-acdb-4dfe-88dc-38538486c9b3
relation.isAuthorOfPublication.latestForDiscovery790fdd33-acdb-4dfe-88dc-38538486c9b3

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