Publication
Insights into the bioactive composition, antioxidant properties and In vitro cell effects of disphyma crassifolium
| dc.contributor.author | Silva, Ana Margarida | |
| dc.contributor.author | Moreira, Manuela M. | |
| dc.contributor.author | Teixeira, Filipa | |
| dc.contributor.author | Delerue-Matos, Cristina | |
| dc.contributor.author | Rodrigues, Francisca | |
| dc.contributor.author | Ferraz, Ricardo | |
| dc.contributor.author | Salazar, Miguel | |
| dc.date.accessioned | 2024-05-29T13:34:38Z | |
| dc.date.available | 2024-05-29T13:34:38Z | |
| dc.date.issued | 2024-04-17 | |
| dc.description.abstract | Disphyma crassifolium, commonly known as sea fingers, is a halophyte plant recently introduced in gourmet cuisine. The present study aims to extract the bioactive compounds of D. crassifolium using ultrasound-assisted extraction and employing green solvents (water and ethanol). The antioxidant/antiradical activities, scavenging capacity against reactive species, phenolic profile, and intestinal effects were evaluated. The highest total phenolic (53.13 mg of gallic acid equivalent (GAE)/g on dry weight (dw)) and flavonoid contents (18.98 mg of catechin equivalent (CE)/g dw) as well as antioxidant (149.69 µmol of ferrous sulphate equivalent (FSE)/g dw) and antiradical capacities (9.37 mg of ascorbic acid equivalent (AAE)/g dw) were achieved for the alcoholic extract. Moreover, the alcoholic extract exhibited an efficient uptake of HOCl (IC50 = 1.97 µg/mL) and ROO• (0.34 µmol of Trolox equivalent (TE)/mg dw). A total of 34 phenolic compounds were identified in the extracts, with flavonols (isorhamnetin-3-O-rutinoside, quercetin-3-O-galactoside, and myricetin), flavanols (catechin), and phenolic acids (gallic and ellagic acids) being the principal classes. The intestinal cell viability assays attested that the alcoholic extract presented the lowest IC50 values (289.82 and 35.77 µg/mL for HT29-MTX and Caco-2), showing probable anticancer activity. These results emphasize the potential of D. crassifolium as a nutraceutical ingredient. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | Silva, A. M., Moreira, M. M., Teixeira, F., Ferraz, R., Salazar, M., Delerue-Matos, C., & Rodrigues, F. (2024). Insights into the bioactive composition, antioxidant properties and in vitro cell effects of Disphyma crassifolium. Foods, 13(8), Artigo 8. https://doi.org/10.3390/foods13081219 | pt_PT |
| dc.identifier.doi | 10.3390/foods13081219 | pt_PT |
| dc.identifier.eissn | 2304-8158 | |
| dc.identifier.uri | http://hdl.handle.net/10400.22/25588 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | MDPI | pt_PT |
| dc.relation | The authors are thankful to Riafresh for providing the samples. Ana Margarida Silva is thankful for the Ph.D. grant (SFRH/BD/144994/2019) financed by POPH-QREN and subsidized by the European Science Foundation and Ministério da Ciência, Tecnologia e Ensino Superior. Manuela M. Moreira (CEECIND/02702/2017) and Francisca Rodrigues (CEECIND/01886/2020) are thankful for their contracts financed by FCT/MCTES—CEEC Individual Program Contract. | pt_PT |
| dc.relation.publisherversion | https://www.mdpi.com/2304-8158/13/8/1219 | pt_PT |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt_PT |
| dc.subject | Sea fingers | pt_PT |
| dc.subject | Ultrasound-assisted extraction | pt_PT |
| dc.subject | Phenolic profile | pt_PT |
| dc.subject | Pro-healthy effects | pt_PT |
| dc.title | Insights into the bioactive composition, antioxidant properties and In vitro cell effects of disphyma crassifolium | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 12 | pt_PT |
| oaire.citation.startPage | 1 | pt_PT |
| oaire.citation.title | Foods | pt_PT |
| oaire.citation.volume | 13(8) | pt_PT |
| person.familyName | Ferraz | |
| person.givenName | Ricardo | |
| person.identifier.ciencia-id | 001E-71CE-F92D | |
| person.identifier.orcid | 0000-0002-1761-117X | |
| person.identifier.rid | G-5639-2011 | |
| person.identifier.scopus-author-id | 24464208500 | |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | article | pt_PT |
| relation.isAuthorOfPublication | a5a8faa7-12a5-4b1c-bced-44c895677397 | |
| relation.isAuthorOfPublication.latestForDiscovery | a5a8faa7-12a5-4b1c-bced-44c895677397 |