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Orientador(es)
Resumo(s)
Quinoxaline-1,4-dioxide (QNX) derivatives are synthetic heterocyclic compounds with multiple biological and pharmacological effects. In this study, we investigated the oxidative status of quinoxaline-1,4-dioxides derivatives in modulating melanoma and glioma cell lines, based on previous results from the research group and their capability to promote cell damage by the production of Reactive Oxygen Species (ROS).
Descrição
Palavras-chave
Quinoxaline-1 4-dioxides derivatives Oxidative stress Radiation resistance Melanoma Glioma Radiosensitizing
Contexto Educativo
Citação
Liliana, S., Pedro, C., Dulce, T., Armanda, M., Gabriela, P., Raquel, S., Mónica, V. (2020). Oxidative Stress Modulation and Radiosensitizing Effect of Quinoxaline-1,4-Dioxides Derivatives. Anti-Cancer Agents in Medicinal Chemistry, 20(1), 111-120. doi:http://dx.doi.org/10.2174/1871520619666191028091547
Editora
Bentham Science