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Biological activities of gedunin—A limonoid from the meliaceae family

2020-01Journal article Open access
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dc.contributor.authorBraga, Teresa M.
dc.contributor.authorRocha, Lídia
dc.contributor.authorChung, Tsz Yan
dc.contributor.authorFerraz Oliveira, Rita
dc.contributor.authorPinho, Cláudia
dc.contributor.authorOliveira, Ana Isabel
dc.contributor.authorMorgado, Joaquim
dc.contributor.authorCruz, Agostinho
dc.date.accessioned2020-01-23T17:20:57Z
dc.date.available2020-01-23T17:20:57Z
dc.date.issued2020-01
dc.description.abstractGedunin is an important limonoid present in several genera of the Meliaceae family, mainly in seeds. Several biological activities have been attributed to gedunin, including antibacterial, insecticidal, antimalarial, antiallergic, anti-inflammatory, anticancer, and neuroprotective effects. The discovery of gedunin as a heat shock protein (Hsp) inhibitor represented a very important landmark for its application as a biological therapeutic agent. The current study is a critical literature review based on the several biological activities so far described for gedunin, its therapeutic effect on some human diseases, and future directions of research for this natural compound.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationBraga, T. M., Rocha, L., Chung, T. Y., Oliveira, R. F., Pinho, C., Oliveira, A. I., Morgado, J., & Cruz, A. (2020). Biological activities of Gedunin—A limonoid from the Meliaceae family. Molecules, 25(3), Artigo 3. https://doi.org/10.3390/molecules25030493
dc.identifier.doi10.3390/molecules25030493pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.22/15363
dc.language.isoporpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.relation.publisherversionhttps://www.mdpi.com/1420-3049/25/3/493pt_PT
dc.subjectGeduninpt_PT
dc.subjectLimonoidpt_PT
dc.subjectMeliaceae familypt_PT
dc.subjectBiological activitypt_PT
dc.subjectBioactive compoundpt_PT
dc.titleBiological activities of gedunin—A limonoid from the meliaceae familypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue3pt_PT
oaire.citation.startPage493pt_PT
oaire.citation.titleMoleculespt_PT
oaire.citation.volume25pt_PT
person.familyNameChung
person.familyNameFerraz Oliveira
person.familyNamePinho
person.familyNameOliveira
person.familyNameCruz
person.givenNameTsz Yan
person.givenNameRita
person.givenNameCláudia
person.givenNameAna Isabel
person.givenNameAgostinho
person.identifier.ciencia-idBD1C-A135-95F3
person.identifier.ciencia-idB91E-9826-5811
person.identifier.ciencia-idFD1F-2E0C-1254
person.identifier.ciencia-id8B1B-A0D9-B6E4
person.identifier.orcid0000-0001-6925-2386
person.identifier.orcid0000-0003-3933-5740
person.identifier.orcid0000-0002-3157-3712
person.identifier.orcid0000-0002-3160-6596
person.identifier.orcid0000-0002-1157-8196
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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relation.isAuthorOfPublication27d1e6a3-6fcf-4dd7-9237-3a6b0baf8ca6
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relation.isAuthorOfPublication01c994b8-cb20-43a8-947c-d2b978283944
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relation.isAuthorOfPublication.latestForDiscovery6c1b7213-1303-47eb-bfa7-ecbef6a9b8d9

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