Repository logo
 
Publication

Potential pathogenic and opportunistic oral bacteria in early life: the role of maternal factors in a portuguese population

2023-01-03Journal article Open access
Simple item page
dc.contributor.authorFernandes, Mariana
dc.contributor.authorAzevedo, Maria João
dc.contributor.authorCampos, Carla
dc.contributor.authorFerreira, Ana Filipa
dc.contributor.authorAzevedo, Álvaro
dc.contributor.authorFalcão-Pires, Inês
dc.contributor.authorZaura, Egija
dc.contributor.authorRamalho, Carla
dc.contributor.authorCampos, Joana
dc.contributor.authorSampaio-Maia, Benedita
dc.date.accessioned2023-03-20T16:44:26Z
dc.date.available2023-03-20T16:44:26Z
dc.date.issued2023-01-03
dc.description.abstractIn early life, maternal factors are of the utmost relevance for oral microbiome acquisition and maturation. Therefore, our study explored the impact of maternal factors, such as saliva and breastmilk colonization, cardiovascular risk factors (CRF), type of delivery, oral health, and caregiving habits on the prevalence of potential pathogenic and opportunistic oral bacteria in early life. A total of 26 healthy mothers, 23 mothers with CRF, and their 50 children were included and samples (child’s oral swabs, mother’s saliva, and breastmilk) were collected 4 to 12 weeks after delivery and inoculated in selective and differential media for detection of non-fastidious Gram-negative and Gram-positive bacteria to isolate potential pathogenic and opportunistic bacteria identified by MALDI-TOF MS (414 isolates). Within mother–child dyads, the same species were identified in 86% of the pairs and potential pathogenic microorganisms from the Staphylococcaceae and Enterobacteriaceae families were found to be statistically significantly concordant between mother–child samples, particularly in the healthy group. Staphylococcus saprophyticus and Stenotrophomonas maltophilia oral colonization in mother–child pairs were associated with the presence of CRF. Breastfeeding was related to the early life oral colonization of Staphylococcus epidermidis in children from healthy mothers and C-section was associated with higher diversity of pathogens, independent of cardiovascular status (p = 0.05). This study reveals the presence of potential oral opportunistic and pathogenic bacteria in early life and highlights the importance of maternal factors in its acquisition.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationFernandes, M., Azevedo, M. J., Campos, C., Ferreira, A. F., Azevedo, Á., Falcão-Pires, I., Zaura, E., Ramalho, C., Campos, J., & Sampaio-Maia, B. (2023). Potential Pathogenic and Opportunistic Oral Bacteria in Early Life: The Role of Maternal Factors in a Portuguese Population. Pathogens, 12(1), 80. https://doi.org/10.3390/pathogens12010080pt_PT
dc.identifier.doi10.3390/pathogens12010080pt_PT
dc.identifier.eissn2076-0817
dc.identifier.urihttp://hdl.handle.net/10400.22/22545
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.relation.publisherversionhttps://www.mdpi.com/2076-0817/12/1/80pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectOral microbiomept_PT
dc.subjectMaternal oral healthpt_PT
dc.subjectMother–child microbiome transmissionpt_PT
dc.subjectOpportunistic/pathogenic bacteriapt_PT
dc.subjectCardiovascular riskpt_PT
dc.titlePotential pathogenic and opportunistic oral bacteria in early life: the role of maternal factors in a portuguese populationpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage13pt_PT
oaire.citation.startPage1pt_PT
oaire.citation.titlePathogenspt_PT
oaire.citation.volume12(1)pt_PT
person.familyNameCampos
person.givenNameCarla
person.identifier.ciencia-idA71C-B158-BC1F
person.identifier.orcid0000-0002-6220-4469
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication2d983798-af3d-467b-a97e-e5629edf5409
relation.isAuthorOfPublication.latestForDiscovery2d983798-af3d-467b-a97e-e5629edf5409

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
ART_Carla Campos.pdf
Size:
1023.84 KB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

ESS - ACSP - Artigos