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Panic disorder and cardiovascular diseases: an overview

dc.contributor.authorMachado, Sergio
dc.contributor.authorSancassiani, Federica
dc.contributor.authorPaes, Flavia
dc.contributor.authorRocha, Nuno
dc.contributor.authorMurillo-Rodriguez, Eric
dc.contributor.authorNardi, Antonio Egidio
dc.date.accessioned2023-12-07T09:10:40Z
dc.date.available2023-12-07T09:10:40Z
dc.date.issued2017-09-12
dc.description.abstractThe association between panic disorder (PD) and cardiovascular diseases (CVD) has been extensively studied in recent years and, although some studies have shown anxiety disorders co-existing or increasing the risk of heart disease, no causal hypothesis has been well established. Thus, a critical review was performed of the studies that evaluated the association between PD and cardiovascular diseases; synthesizing the evidence on the mechanisms mediators that theoretically would be the responsible for the causal pathway between PD and CVD, specifically. This overview shows epidemiological studies, and discusses biological mechanisms that could link PD to CVD, such as pleiotropy, heart rate variability, unhealthy lifestyle, atherosclerosis, mental stress, and myocardial perfusion defects. This study tried to provide a comprehensive narrative synthesis of previously published information regarding PD and CVD and open new possibilities of clinical management and pathophysiological understanding. Some epidemiological studies have indicated that PD could be a risk factor for CVD, raising morbidity and mortality in PD, suggesting an association between them. These studies argue that PD pathophysiology could cause or potentiate CVD. However, there is no evidence in favour of a causal relationship between PD and CVD. Therefore, PD patients with suspicions of cardiovascular symptoms need redoubled attention.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationMachado, S., Sancassiani, F., Paes, F., Rocha, N., Murillo-Rodriguez, E., & Nardi, A. E. (2017). Panic disorder and cardiovascular diseases: An overview. International Review of Psychiatry, 29(5), 436–444. https://doi.org/10.1080/09540261.2017.1357540pt_PT
dc.identifier.doi10.1080/09540261.2017.1357540pt_PT
dc.identifier.eissn1369-1627
dc.identifier.issn0954-0261
dc.identifier.urihttp://hdl.handle.net/10400.22/24092
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherTaylor & Francispt_PT
dc.relation.publisherversionhttps://www.tandfonline.com/doi/full/10.1080/09540261.2017.1357540pt_PT
dc.subjectPanic disorderpt_PT
dc.subjectCardiovascular diseasept_PT
dc.subjectPleiotropypt_PT
dc.subjectHeart ratept_PT
dc.subjectVariabilitypt_PT
dc.subjectUnhealthypt_PT
dc.subjectLifestyle and atherosclerosispt_PT
dc.titlePanic disorder and cardiovascular diseases: an overviewpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage444pt_PT
oaire.citation.startPage436pt_PT
oaire.citation.titleInternational Review of Psychiatrypt_PT
oaire.citation.volume29 (5)pt_PT
person.familyNameRocha
person.givenNameNuno
person.identifier192266
person.identifier.ciencia-idAE16-A494-5F8B
person.identifier.orcid0000-0002-3139-2786
person.identifier.ridM-9821-2013
person.identifier.scopus-author-id32867975300
rcaap.rightsclosedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication9e940914-601a-4978-8d5b-74e5ade7ada7
relation.isAuthorOfPublication.latestForDiscovery9e940914-601a-4978-8d5b-74e5ade7ada7

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