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- HUMMR Acts as a “roadblock” for mitochondrial transport in Alzheimer’s diseasePublication . Correia, Sónia C.; Pinho, Tiffany S.; Zhu, Xiongwei; Perry, George; Moreira, Paula I.Alterations in axonal transport of mitochondria play a critical role in Alzheimer’s disease (AD) neuropathology; however, the molecular mechanisms involved remain unexplored (Li et al., 2009).