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- Colouring applications of microalgae and cyanobacteria photosynthetic pigments: Challenges for industrial and market acceptancePublication . Reimão, Mariana; Almeida, Liliana; Ramos, Cristiana; Eusébio, Nádia; Martins, Rosário; Silva, Manuela Vieira da; Vasconcelos, Vítor; Freitas, Marisa; Freitas, Marisa; Vieira da Silva, Manuela; Martins, Rosario; REIMÃO BORGES LOPES DA SILVA, MARIANAMicroalgae and cyanobacterial photosynthetic pigments possess immense potential for sustainable colouring applications in industries such as food, feed, cosmetics and textiles, primarily because of their vibrant colours, safety and eco-friendliness. These photosynthetic pigments align with the growing demand for eco-conscious products. However, substantial challenges persist at the industrial level, particularly in scaling up production and achieving acceptance in niche markets. This review highlights the critical roles of abiotic factors such as light quality, temperature, pH, nutrient availability and salinity in enhancing pigment production using conventional production methods. Additionally, issues related to the cost, purity and stability of the pigments must be addressed to facilitate broader acceptance. Looking forward, the focus must be on developing innovative cultivation techniques that optimise and define the abiotic conditions most favourable for maximum pigment production or even incorporate genetic engineering tools. Additionally, exploring untapped species from inhospitable environmental sources and integrating the residual biomass through biorefinery processes represent effective approaches for enhancing the sustainability of microalgae and cyanobacterial pigment production on an industrial scale. Overcoming these barriers utilising targeted research and industry collaboration as well as fostering market acceptance is essential for fully harnessing the potential of these natural pigments and driving the transition towards more sustainable industrial colouring practices.
- Executive function in gambling disorder: A meta-analysis on neuropsychological evidencePublication . Peixoto, Miguel; Dores, Artemisa; Monteiro, Maria; Marques, António; Barbosa, Fernando; Pereira da Silva Marques, António José; Dores, Artemisa; de Faria Távora Moreira Peixoto, MiguelGambling disorder (GD) is associated with defcits in various cognitive functions. Specifcally for executive function (EF), previous fndings are inconsistent, despite defcits being reported for shifting, inhibition, planning, and working memory domains. Although a worse performance in EF measures related to GD severity is often reported, there is a need to clarify current evidence. This study aims to systematically review and perform a meta-analysis to clarify the association between EF defcits and GD. The current study followed the preferred reporting items for systematic reviews and meta-analyses protocols. The meta-analysis used a random efects model and robust variance estimation to analyze the data, using Hedge’s g to report efect sizes. A total of 21 studies were systematically reviewed, of which 17 were included for meta-analysis. Meta-analysis was performed for shifting, inhibition, planning, and verbal fuency. Due to a lower number of studies, working memory data was systematically reviewed, but no meta-analysis was performed. Significant efect sizes were found for shifting and inhibition, indicative of defcits in participants with GD. No signifcant defcits were found for the other EF domains. Working memory results revealed inconsistent evidence, even when divided into verbal and visuospatial modalities. There is enough evidence of defcits in shifting and inhibition in participants with GD. However, better sample characterization should be considered in future studies to better understand the sources of potential heterogeneity. Consideration of gambling severity as a continuous variable could allow for a more detailed analysis of EF alterations across the various degrees of GD.
- Impact of per- and polyfluorinated alkyl substances (PFAS) on the marine environment: Raising awareness, challenges, legislation, and mitigation approaches under the One Health conceptPublication . Bilela, Lada Lukić; Matijošytė, Inga; Krutkevičius, Jokūbas; Alexandrino, Diogo A.M.; Safarik, Ivo; Burlakovs, Juris; Gaudêncio, Susana P.; Carvalho, Maria F.; Alexandrino, DiogoPer- and polyfluorinated alkyl substances (PFAS) have long been known for their detrimental effects on the ecosystems and living organisms; however the long-term impact on the marine environment is still insufficiently recognized. Based on PFAS persistence and bioaccumulation in the complex marine food network, adverse effects will be exacerbated by global processes such as climate change and synergies with other pollutants, like microplastics. The range of fluorochemicals currently included in the PFAS umbrella has significantly expanded due to the updated OECD definition, raising new concerns about their poorly understood dynamics and negative effects on the ocean wildlife and human health. Mitigation challenges and approaches, including biodegradation and currently studied materials for PFAS environmental removal are proposed here, highlighting the importance of ongoing monitoring and bridging research gaps. The PFAS EU regulations, good practices and legal frameworks are discussed, with emphasis on recommendations for improving marine ecosystem management.