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- Medication review improves pain management and quality of life in chronic pain: a pilot randomized controlled studyPublication . Duarte, Nuno; Martins, João Paulo; García-Domingo, Mónica; A. García-Pedraza, Jose; Santos, Marlene; Santos, Marlene; Oliveira Martins, João Paulo; Duarte, NunoChronic pain is a complex condition that benefits from a multidisciplinary approach. This pilot parallel-group single-blinded randomized controlled study evaluated the feasibility, acceptability and adherence by patients and physicians of pharmacist-led medication review on chronic pain patients. Trends in pain intensity, quality of life and patient satisfaction were examined. Twenty adults were recruited from two primary care units in Porto, Portugal, and randomly assigned to either the medication review (MR) group, (n=10) using the Dader method, or the usual care (UC) group, (n=10) and given general advice, for 16-weeks. Pain intensity decreased by 2.07 (MR group) and increased by 0.52 (UC group), yielding an adjusted mean difference of 2.77 (95% CI, -4.93 to -0.62; p=0.008). Pain relief was reported by 62.5% in the MR group versus 37.5% in UC (p=0.357). The MR group showed significant improvement in physical functioning (p=0.019) and higher treatment satisfaction (p=0.029). The acceptance rate of MR interventions was 71%, which resolved 63% of negative medication outcomes. Acceptability was high (>90% of planned interviews). Conducting pharmacist led MR for chronic pain management in primary care is feasible and well accepted by patients and physicians. Observed trends toward improved pain and QoL warrant confirmation in a larger trial. This pilot trial was registered in clinicaltrials.gov (NCT06997861).
- A virtual reality game to support cognitive stimulation in elderly people with Alzheimer's and Mild DementiaPublication . Barbosa, Alice; Melro, Henrique; Pacheco, Rodrigo; Almeida, Raquel Simões; Teixeira, Bruno; Sá, Vitor J.; Simões de Almeida, Raquel; Sá, Vítor J.This article presents the development of ReLembra, an immersive Virtual Reality game designed to support elderly people with Alzheimer's and mild dementia in preserving their cognitive abilities, that is, in preventing activities and some motor functions for daily life. Through interactive activities in calm and familiar virtual environments, the games promote the stimulation of memory, language, organization and spatial orientation. The application was developed in the Unity 3D tool and optimized for the Meta Quest 3 device. Tests were carried out with five participants, evaluating presence (IPQ), cybersickness (SSQ), usability (SUS) and performance metrics. The results indicate high usability and excellent acceptance. However, some limitations related to the digital literacy of users and the difficulty in distinguishing between the virtual and the real world were identified. This project represents an innovative and promising tool to support health professionals and caregivers, with potential for future expansion.
