Browsing by Issue Date, starting with "2025-06-13"
Now showing 1 - 3 of 3
Results Per Page
Sort Options
- Efficacy and safety of Tocilizumab in the treatment of Rheumatoid Arthritis: An umbrella reviewPublication . Silva, David; Moreira, Fernando; Santos, Marlene; Moreira, FernandoTocilizumab (TCZ) is a humanized immunoglobulin G1 monoclonal antibody that targets and inhibits the interleukin-6 (IL-6) receptor. As a selective inhibitor of this cytokine, TCZ offers a targeted approach in managing inflammatory conditions. Given its specificity and potential therapeutic benefits, this article aims to provide a comprehensive summary of the efficacy and safety of TCZ in the treatment of RA.
- Pharmacological approaches in Amyotrophic Lateral Sclerosis: A systematic review of clinical trials on efficacy, survival, and safety profilesPublication . Tomé, Pedro; Moreira, Fernando; Santos, Marlene; Moreira, Fernando; Santos, MarleneAmyotrophic lateral sclerosis is a progressive neurodegenerative disease that results in the deterioration of neuromuscular connections, with no effective treatment currently available.
- Exploring the role of oral antidiabetic medications as adjuncts in depression treatmentPublication . Santos, Marlene; Santos, Angela; Jesus, Ângelo; Jesus, ÂngeloDepression is a complex and multifaceted disorder with a poorly defined etiology and numerous risk factors. Despite the availability of several antidepressant classes, many treatments have limitations that compromise their effectiveness and impact patients’ quality of life.