Repository logo

Browsing by Issue Date, starting with "2022-02-15"

Filter results by year or month
Now showing 1 - 2 of 2
  • The impact of the COVID-19 pandemic on people with lived experience of mental illness integrated into community-based psychosocial rehabilitation structures in Portugal
    Publication . Costa, Ana; Santos, Marta; Simões de Almeida, Raquel; Monteiro, Fátima; Marques, António
    To analyze the prevalence and impact of SARS-CoV-2 infection in people with lived experience of mental illness integrated into community-based psychosocial rehabilitation structures in Portugal. One hundred and thirty-nine people with lived experience of mental illness integrated into community-based psychosocial rehabilitation structures in Portugal answered an online survey that included dimensions related to COVID-19 pandemic prevalence, routine/lifestyle, social support, access to health care, mental health and well-being during the pandemic and confinement, and life satisfaction and postpandemic future expectations. The results point to a low prevalence of SARS-CoV-2 infections in this sample. High levels of resilience and mental well-being were identified in the individuals. We also found that participants were satisfied with the social support during this phase and their routine/lifestyle. The study showed that the COVID-19 pandemic seems not to have had a significant negative impact on people with experience of mental illness integrated into community-based psychosocial rehabilitation structures in Portugal. However, more research in this field should be done in the future.
    2022-02-15Journal article Open access Show more
  • Cannabidiol and terpene formulation reducing SARS-CoV-2 infectivity tackling a therapeutic strategy
    Publication . Santos, Susana; Barata, Pedro; Charmier, Adilia; Lehmann, Inês; Rodrigues, Suzilaine; Melosini, Matteo M.; Pais, Patrick J.; Sousa, André P.; Teixeira, Catarina; Santos, Inês; Rocha, Ana Catarina; Baylina, Pilar; Fernandes, Ruben
    In late 2019, COVID-19 emerged in Wuhan, China. Currently, it is an ongoing global health threat stressing the need for therapeutic compounds. Linking the virus life cycle and its interaction with cell receptors and internal cellular machinery is key to developing therapies based on the control of infectivity and inflammation. In this framework, we evaluate the combination of cannabidiol (CBD), as an anti-inflammatory molecule, and terpenes, by their anti-microbiological properties, in reducing SARS-CoV-2 infectivity. Our group settled six formulations combining CBD and terpenes purified from Cannabis sativa L, Origanum vulgare, and Thymus mastichina. The formulations were analyzed by HPLC and GC-MS and evaluated for virucide and antiviral potential by in vitro studies in alveolar basal epithelial, colon, kidney, and keratinocyte human cell lines.
    2022-02-15Journal article Open access Show more