Repository logo

Browsing by Issue Date, starting with "2020-10-05"

Filter results by year or month
Now showing 1 - 2 of 2
  • How the COVID-19 Pandemic Impacted Oncological Molecular Diagnosis: A Picture from a National Reference Center for Molecular Pathology
    Publication . Pinto, Daniel; Cirnes, Luís; Pinto, Regina; Pina, Maria João; Giancarlo, Troncone; Schimitt, Fernando
    The Portuguese healthcare system had to adapt at short notice to the COVID-19 pandemic. We implemented workflow changes to our molecular pathology laboratory, a national reference center, to maximize safety and productivity. We assess the impact this situation had on our caseload and what conclusions can be drawn about the wider impact of the pandemic in oncological therapy in Portugal. Material and Methods. We reviewed our database for all oncological molecular tests requested between March and April of 2019 and 2020.
    2020-10-05Journal article Open access Show more
  • A typological study of portuguese mortality from non-communicable diseases
    Publication . Nascimento, Ana Paula; Prudêncio, Cristina; Vieira, Mónica; Pimenta, Rui; Bacelar-Nicolau, Helena
    The most common non-communicable diseases, such as cardiovascular diseases and cancer, are a problem in global and national growth. The World Health Organization considers it a priority to study the specific causes of these diseases for trend monitoring. The aim of this paper is to identify a hierarchy of clusters of Portuguese mortality by non-communicable diseases using the agglomerative hierarchical cluster analysis. The Euclidean distance with complete linkage and average linkage criteria are used. These methods identify six clusters with both criteria, indicating some order of disease severity in the way clusters joint together. Special attention should be given to diseases in the last two clusters, where the last one is formed by ischemic heart disease, cerebrovascular diseases and larynx / trachea / bronchi and lung malignant tumor, all for males. In fact, these clustering results show that male gender seems to be a risk factor for at least two groups of the non-communicable diseases. Other suggested risk factors and / or pathophysiological mechanisms that in a direct or indirect way may enhance the common development of the pathologies found in the clusters arising from this study should also be an object of priority study.
    2020-10-05Journal article Open access Show more