Browsing by Author "Soares, S."
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- Parameters optimization of filtered back projection in Myocardial Perfusion Imaging reconstructionPublication . Metelo, Luís Francisco; Cunha, L.; Vieira, Domingos; Fonseca, A.; Tavares, A.; Soares, S.; Amorim, I.; Castro, R.; Abrantes, A. M.; Botelho, M. F.Nowadays, even if it is noticed an increasingly wider use of Iterative Methods (IM), a significant number of NM Departments is still routinely using Filtered Backprojection (FBP) as the method of choice in what concerns image processing in MPI. Several authors recommend the use of same filter parameters, no matter what the patient physical characteristics are.
- Study of the influence of patient hydration in bone ScintigraphyPublication . Ferreira, S.; Cunha, L.; Fonseca, A.; Vieira, Domingos; Lemos, Joana; Matias, M.; Osorio, S.; Soares, S.; Silva, J. A.; Amorim, M. I.; Castro, R.; Metelo, Luís FranciscoBone Scintigraphy is a noninvasive and very sensitive Nuclear Medicine diagnostic method in detecting early bone lesions. Between the important technical details to consider when dealing with patient preparation there is the hydration level.
- The effect of shape of gold nanoparticles in cytotoxicity of prostate cancer cell linesPublication . Soares, S.; Guerreiro, S.G.; Sales, M.G.F.; Correa-Duarte, M.; Fernandes, RúbenGold nanoparticles (AuNP) can be applied in medicine to treat many diseases, such as cancer. Over the years, they have attracted a lot of interest for therapies. In this study, we synthetized three different shapes of gold nanoparticles – spherical, stars and rods and analyzed their cytotoxicity in prostate cancer cell lines (PC3, DU145 and LNCaP). Cells were treated with different concentrations of gold nanoparticles, from 0 to 1.0 mM during 24h. The results showed that gold nanoparticles were nontoxic to concentration until 1.0 mM.