Browsing by Author "Pinto, Liliana"
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- A microfluidics technique to evaluate Staphylococcus aureus adhesion to micropatterned silica surfacesPublication . Pinto, Liliana; Monteiro, Fernando Jorge; Carvalho, ÂngelaPostoperative complications like poor osteointegration or bacterial adhesion to bone implants are the most common causes that lead to implant failure. Micropatterned surfaces have been used to improve implant osteointegration as they have shown to promote enhanced cellular attachment, proliferation and differentiation. It is well established that modifying the surface topography of a biomaterial has a positive effect on regeneration. However, a concern related to using implants with greater surface area and roughness is that bacterial adhesion might be increased. This study intends to evaluate the bacterial adhesion of S. aureus to micropatterned silica surfaces, proposed to be applied as bioactive coatings for bioinert hard-ceramic implants.