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Browsing by Author "Gomes, Mariana"

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  • Adapted chester step test can have maximal response characteristics for the assessment of exercise capacity in young women
    Publication . Vilarinho, Rui; Mendes, Ana Rita; Gomes, Mariana; Ferreira, Rui; Costa, Fabiola; Machado, Marcela; Neves, Márcia; Caneiras, Cátia; Mesquita Montes, António
    Chester step test (CST) estimates the exercise capacity through a submaximal response, which can limit its application in the prescription of exercise. This study aimed to assess whether an adaptation of the CST (with a progressive profile) can have maximal response characteristics in young women and compare it to the incremental shuttle walk test (ISWT). Another aim was to determine its within-day test–retest reliability. A cross-sectional study was conducted with 25 women (20.3 ± 1.5 years) who performed the field tests twice on two different days (48 h apart).
    2021-03-10Journal article Open access Show more
  • Eficácia da osteopatia em adultos com doença de refluxo gastroesofágico: revisão sistemática
    Publication . Reigoto, Cláudia; Gomes, Mariana; Carmo, Patrícia; Aguiar, Sílvia; Campelo, Natalia; Sousa, Helena
    A doença do refluxo gastroesofágico (DRGE) é caracterizada pelo refluxo anormal do conteúdo gástrico para o esófago, sendo dos distúrbios gastrointestinais mais comuns na prática clínica osteopática. O tratamento manipulativo osteopático (TMO) tem vindo a ser recomendado na abordagem da DRGE. Contudo, existe pouca evidência que comprove o efeito desta intervenção na DRGE. Realizar uma análise crítica sobre a eficácia da osteopatia na redução da semiologia em adultos diagnosticados com DRGE, procurando evidenciar qual o tratamento osteopático que melhor se adequa.
    2022-02-25Conference object Open access Show more
  • Subacute effects of the thiodicarb pesticide on target organs of male wistar rats: biochemical, histological, and flow cytometry studies
    Publication . Dias, Elsa; Gomes, Mariana; Domingues, Catarina; Ramalheira, Elmano; Morais, Simone; Pereira, Maria de Lourdes
    Thiodicarb, a carbamate pesticide widely used on crops, may pose several environmental and health concerns. This study aimed to explore its toxicological profile on male rats using hematological, biochemical, histopathological, and flow cytometry markers. Exposed animals were dosed daily at 10, 20, or 40 mg/kg/body weight (group A, B, and C, respectively) during 30 d. No significant changes were observed in hematological parameters among all groups. After 10 d, a decrease of total cholesterol levels was noted in rats exposed to 40 mg/kg. Aspartate aminotransferase (AST) activity increased (group A at 20 d; groups A and B at 30 d) and alkaline phosphatase (ALP) (group B at 30 d) activity significantly reduced. At 30 d a decrease of some of the other evaluated parameters was observed with total cholesterol and urea levels in group A as well as total protein and creatinine levels in groups A and B. Histological results demonstrated multi-organ dose-related damage in thiodicarb-exposed animals, evidenced as hemorrhagic and diffuse vacuolation in hepatic tissue; renal histology showed disorganized glomeruli and tubular cell degeneration; spleen was ruptured with white pulp and clusters of iron deposits within red pulp; significant cellular loss was noted at the cortex of thymus; and degenerative changes were observed within testis. The histopathologic alterations were most prominent in the high-dose group. Concerning flow cytometry studies, an increase of lymphocyte number, especially T lymphocytes, was seen in blood samples from animals exposed to the highest dose. Taken together, these results indicate marked systemic organ toxicity in rats after subacute exposure to thiodicarb.
    2013Journal article Open access Show more