Browsing by Author "Ferreira, Sofia"
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- Bone injury and repair trigger central and peripheral NPY Neuronal PathwaysPublication . Alves, Cecília J.; Alencastre, Inês S.; Neto, Estrela; Ribas, João; Ferreira, Sofia; Vasconcelos, Daniel M.; Sousa, Daniela M.; Summavielle, Teresa; Lamghari, MeriemBone repair is a specialized type of wound repair controlled by complex multi-factorial events. The nervous system is recognized as one of the key regulators of bone mass, thereby suggesting a role for neuronal pathways in bone homeostasis. However, in the context of bone injury and repair, little is known on the interplay between the nervous system and bone. Here, we addressed the neuropeptide Y (NPY) neuronal arm during the initial stages of bone repair encompassing the inflammatory response and ossification phases in femoral-defect mouse model. Spatial and temporal analysis of transcriptional and protein levels of NPY and its receptors, Y1R and Y2R, reported to be involved in bone homeostasis, was performed in bone, dorsal root ganglia (DRG) and hypothalamus after femoral injury. The results showed that NPY system activity is increased in a time- and space-dependent manner during bone repair. Y1R expression was trigged in both bone and DRG throughout the inflammatory phase, while a Y2R response was restricted to the hypothalamus and at a later stage, during the ossification step. Our results provide new insights into the involvement of NPY neuronal pathways in bone repair.
- Trust in human robot interaction: a literature reviewPublication . Ferreira, Sofia; Silva, Ana Sofia; Pinto, Ana; Santos, Joana; Carvalhais, CarlosThe presence of collaborative robots (or cobots) in workplaces will become increasingly common due to the need to ensure the health and safety of workers and to make production systems more efficient and flexible. To ensure good performance in human-robot interaction, it is essential that there is trust on the part of the human in this technology. Objectives: Thus, the main objective of this study was to identify the factors that may influence human-robot interaction through a literature review. Materials and Methods: To accomplish this objective, the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews method was applied. The scientific databases used were Pubmed and Web Of Science. Results and Discussion: The literature search resulted in a total of 63 articles, 5 of which were included for analysis after applying the eligibility criteria. The factor "errors made by the robot" was the most reported in the included studies. Correlation between the different factors impacting trust was also observed. Conclusions: The success of human-robot interaction depends on the trust that the human places in the technology. However, it is essential to develop further studies on trust in industrial settings.