Percorrer por autor "Almeida, Maria"
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- Development of a biossensor for prostate cancer using sarcosine as biomarkerPublication . Almeida, Maria; Carneiro, Liliana; Sales, M. GoretiProstate cancer is the most common type of tumor disease in men, making the development of new methods that allow an earlier detection extremely important. One of these methods concerns the use of biosensors to diagnose specific biomarkers for this type of cancer. Biomarkers could be amino acids, proteins or nucleic acids. In this work, the amino acid sarcosine was selected for biosensor development, making use of a molecularly-imprinted polymer (MIP) as biorecognition element. In healthy persons, sarcosine is not present or occurs in negligible concentrations in urine in heathy individuals, but individuals with prostate cancer are expected tohave higher concentrations of sarcosine. In turn, growing interest in the integration of MIP materials in biosensors has led researchers to design novel formats for electrochemical sensors. MIPs are a class of cross-linked polymers with specific recognition sites that are complimentary in shape, size and binding groups to the template.
- Eficácia da intervenção da osteopatia nas disfunções ginecológicas: uma revisão sistemáticaPublication . Fernandes, Ângela; Ferreira, Inês; Almeida, Maria; Boaventura, Maria Francisca; Sousa, Helena; Campelo, NataliaOs distúrbios ginecológicos apresentam elevada prevalência e têm como possíveis consequências o aumento da dor e a diminuição da qualidade de vida. Apesar do tratamento ser maioritariamente farmacológico, cada vez mais a osteopatia se tem afirmado como uma forma de tratamento válida e eficaz. Sistematizar os ensaios clínicos randomizados de forma a verificar a eficácia da intervenção osteopática na dor e qualidade de vida de mulheres com distúrbios ginecológicos em idades compreendidas entre o período pós-menarca e pré-menopausa.
- Physiopathological effects of electric current on the human body and the protection against electric shocksPublication . Carvalho, José António Beleza; Beleza Carvalho, José António; Almeida, Maria; Silva, Catarina; Costa, CarolinaIn electrical installations and equipment, electric current preferentially flows through metallic circuits that offer it less opposition, that is, less electrical resistance. In the human body, electric current also seeks to flow through paths with less electrical resistance, and may be diverted inside the body, damaging surrounding organs and tissues. Its path and the magnitude of the current influence the type of injuries associated with electrical accidents, usually burns, which can be internal and external. In all electrical installations, there is a need and obligation to implement effective protection systems, with the aim of operating them under safe conditions. In Low Voltage Electrical Installations (LVEI), the protection measures that must be considered are overcurrent protection, overvoltage protection, but fundamentally the protection of people from the risk of electrocution, avoiding pathophysiological effects that can be irreversible.