Repository logo
 
Publication

Measurement of optical properties of normal and pathological human liver tissue from deep-UV to NIR

2020Conference object Restricted access
Simple item page
dc.contributor.authorCarneiro, Isa
dc.contributor.authorCarvalho, Sónia
dc.contributor.authorHenrique, Rui
dc.contributor.authorOliveira, Luís
dc.contributor.authorTuchin, Valery V.
dc.date.accessioned2021-04-22T10:41:02Z
dc.date.embargo2100
dc.date.issued2020
dc.description.abstractThe interest of using light in clinical practice is increasing strongly and many applications work at various wavelengths from the ultraviolet to the infrared. Due to this great range of applications, the determination of the optical properties of biological tissues in a wide spectral range becomes of interest. The liver is an important organ, since it has a major role in the human body and various pathologies are known to develop within it. For these reasons, this study concerns the estimation of the optical properties of human normal and pathological (metastatic carcinoma) liver tissues between 200 and 1000 nm. The obtained optical properties present the expected wavelength dependencies for both tissues – the refractive index, the absorption and the scattering coefficients decrease with the wavelength and the anisotropy and light penetration depth increase with the wavelength. Although similar behavior was observed for the various properties between the normal and pathological tissues, evidence of smaller blood content in the pathological tissues was found. A possible explanation is that the cancer cells destroy liver’s vasculature and internal architecture, providing though a reduction in the blood content. For low wavelengths, it was observed a matching between the scattering and the reduced scattering coefficients, which implies a nearly zero anisotropy in that range. The scattering coefficient decreases from nearly 140 cm-1 (at 200 nm) to 80 cm-1 (at 1000 nm) for the normal liver and from nearly 140 cm-1 (at 200 nm) to 95 cm-1 (at 1000 nm) for the pathological tissue.pt_PT
dc.description.sponsorshipThe work of Luís Oliveira was supported by the Portuguese Grant FCT—UID/EQU/04730/2019 and the work of Valery Tuchin was supported by the Russian Government Grant 14. Z50.31.0044.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1117/12.2554877pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.22/17863
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherSPIEpt_PT
dc.relationUID/EQU/04730/201pt_PT
dc.relation.publisherversionhttps://www.spiedigitallibrary.org/conference-proceedings-of-spie/11363/2554877/Measurement-of-optical-properties-of-normal-and-pathological-human-liver/10.1117/12.2554877.short?SSO=1pt_PT
dc.subjectHuman liverpt_PT
dc.subjectCancerpt_PT
dc.subjectAbsorption coefficientpt_PT
dc.subjectScattering coefficientpt_PT
dc.subjectReduced scattering coefficientpt_PT
dc.subjectScattering anisotropy factorpt_PT
dc.subjectLlight penetration depthpt_PT
dc.subjectInverse adding doubling methodpt_PT
dc.titleMeasurement of optical properties of normal and pathological human liver tissue from deep-UV to NIRpt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlaceFrancept_PT
oaire.citation.endPage14pt_PT
oaire.citation.startPage1pt_PT
oaire.citation.titleSPIE Photonics Europe, 2020, Online Onlypt_PT
oaire.citation.volume11363pt_PT
person.familyNameOliveira
person.givenNameLuís
person.identifier414820
person.identifier.ciencia-idC312-F342-BD23
person.identifier.orcid0000-0003-0667-3428
person.identifier.ridB-7198-2017
person.identifier.scopus-author-id55853723900
rcaap.rightsclosedAccesspt_PT
rcaap.typeconferenceObjectpt_PT
relation.isAuthorOfPublication4e2de4d7-142a-400f-8dbf-cd0ff9551093
relation.isAuthorOfPublication.latestForDiscovery4e2de4d7-142a-400f-8dbf-cd0ff9551093

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
COM15_CIETI_2020.pdf
Size:
804.11 KB
Format:
Adobe Portable Document Format
Download

Collections

ISEP – CIETI – Comunicações em eventos científicos
ISEP – DFI – Comunicações em eventos científicos