A factorial design for optimization of the analytical variables on the development of a genoassay for the transgenic soybean detection

Ramos-Jesus, J.; Barroso, M. Fátima; M. S. Silva, Luís; Pereira, C.; Freire, C.; de-los- Santos-Álvarez, N.; Leite, José Roberto S.A.; Delerue-Matos, Cristina

http://hdl.handle.net/10400.22/13105

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Authors

de-los- Santos-Álvarez, N.

Leite, José Roberto S.A.

Delerue-Matos, Cristina

Abstract(s)

At the laboratory, analytical method optimizations are performed to achieve the maximum sensitivity and selectivity. Routinely, this procedure is carried out by optimizing one-factor-at-a-time approach until there is no further improvement, where each experimental parameter is optimized separately and independently of the other factors.