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Refractive Index Matching Efficiency in Colorectal Mucosa Treated With Glycerol

2021Journal article Restricted access
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dc.contributor.authorGomes, Nelma M.
dc.contributor.authorTuchin, Valery V.
dc.contributor.authorOliveira, Luís
dc.date.accessioned2022-02-10T16:56:01Z
dc.date.embargo2031
dc.date.issued2021
dc.description.abstractIn this paper, we describe the study of the kinetics and efficiency of the refractive index matching mechanism created by highly concentrated glycerol solutions in human normal and pathological colorectal mucosa tissues. Considering the wavelength range between 200 and 1000 nm, higher efficiency was obtained for the pathological mucosa, which shows a decreasing efficiency with increasing wavelength. The normal mucosa presents similar values in the deep-ultraviolet and in the near-infrared. Minimal efficiency values of 1% and 1.5% were obtained in the normal and pathological mucosa at 266 nm (combined absorption of DNA/RNA and myoglobin/hemoglobin bands at 260 and 274 nm) and local maxima of 2.9% and 3.8% were obtained in the same tissues at 570 nm. The diffusion time of glycerol was estimated as 417.3±5.2 s in normal mucosa and 504.9±3.8 s in pathological mucosa, suggesting that less molecules are necessary in the pathological tissue to produce a higher magnitude RI matching.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationGomes, N.M., Tuchin, V.V., Oliveira, L. Refractive index matching efficiency in colorectal mucosa treated with glycerol. IEEE J. Sel. Top. Quant. Elect., vol. 27, no. 4, 7200808.pt_PT
dc.identifier.doi10.1109/JSTQE.2021.3050208pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.22/19902
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherIEEEpt_PT
dc.relation.publisherversionhttps://ieeexplore.ieee.org/document/9319197pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/pt_PT
dc.subjectTissue spectroscopypt_PT
dc.subjectOptical clearingpt_PT
dc.subjectColorectal cancerpt_PT
dc.subjectCollimated transmittancept_PT
dc.subjectRefractive index matchingpt_PT
dc.subjectLight scatteringpt_PT
dc.titleRefractive Index Matching Efficiency in Colorectal Mucosa Treated With Glycerolpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage8pt_PT
oaire.citation.issue4pt_PT
oaire.citation.startPage1pt_PT
oaire.citation.titleIEEE Journal of Selected Topics in Quantum Electronicspt_PT
oaire.citation.volume27pt_PT
person.familyNameOliveira
person.givenNameLuís
person.identifier414820
person.identifier.ciencia-idC312-F342-BD23
person.identifier.orcid0000-0003-0667-3428
person.identifier.ridB-7198-2017
person.identifier.scopus-author-id55853723900
rcaap.rightsclosedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication4e2de4d7-142a-400f-8dbf-cd0ff9551093
relation.isAuthorOfPublication.latestForDiscovery4e2de4d7-142a-400f-8dbf-cd0ff9551093

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