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A robust ex vivo method to evaluate the diffusion properties of agents in biological tissues

2019Journal article Restricted access
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dc.contributor.authorCarneiro, Isa
dc.contributor.authorCarvalho, Sónia
dc.contributor.authorHenrique, Rui
dc.contributor.authorOliveira, Luís
dc.contributor.authorTuchin, Valery V.
dc.date.accessioned2021-02-25T16:59:04Z
dc.date.embargo2120
dc.date.issued2019
dc.description.abstractA robust method is presented for evaluating the diffusion properties of chemicals in ex vivo biological tissues. Using this method that relies only on thickness and collimated transmittance measurements, the diffusion properties of glycerol, fructose, polypropylene glycol and water in muscle tissues were evaluated. Amongst other results, the diffusion coefficient of glycerol in colorectal muscle was estimated with a value of 3.3 × 10-7 cm2 /s. Due to the robustness and simplicity of the method, it can be used in other fields of biomedical engineering, namely in organ cryoprotection and food industry.pt_PT
dc.description.sponsorshipMinistry of Science and Higher Education of the Russian Federation, Grant/Award Number: 08‐08; Russian Foundation for Basic Research, Grant/Award Number: 17‐00‐00275 (17‐00‐00272); Portuguese Foundation for Science and Technology, Grant/Award Number: FCT‐UID/EQU/04730/2013pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1002/jbio.201800333pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.22/17166
dc.language.isoengpt_PT
dc.publisherWileypt_PT
dc.relation.publisherversionhttps://onlinelibrary.wiley.com/doi/full/10.1002/jbio.201800333pt_PT
dc.subjectCollimated transmittancept_PT
dc.subjectColorectal tissuespt_PT
dc.subjectDiffusion propertiespt_PT
dc.subjectMusclept_PT
dc.subjectOptical clearingpt_PT
dc.titleA robust ex vivo method to evaluate the diffusion properties of agents in biological tissuespt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FEQU%2F04730%2F2013/PT
oaire.citation.issue4pt_PT
oaire.citation.startPagee201800333pt_PT
oaire.citation.titleJournal of Biophotonicspt_PT
oaire.citation.volume12pt_PT
oaire.fundingStream5876
person.familyNameOliveira
person.givenNameLuís
person.identifier414820
person.identifier.ciencia-idC312-F342-BD23
person.identifier.orcid0000-0003-0667-3428
person.identifier.ridB-7198-2017
person.identifier.scopus-author-id55853723900
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsclosedAccesspt_PT
rcaap.typearticlept_PT
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relation.isAuthorOfPublication.latestForDiscovery4e2de4d7-142a-400f-8dbf-cd0ff9551093
relation.isProjectOfPublicationacbdf6e2-0436-4e8e-bcae-3b2703ce65b3
relation.isProjectOfPublication.latestForDiscoveryacbdf6e2-0436-4e8e-bcae-3b2703ce65b3

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