Repository logo
 
Publication

Enhanced Ultraviolet Spectroscopy by Optical Clearing for Biomedical Applications

2021Journal article Restricted access
Simple item page
dc.contributor.authorCarneiro, Isa
dc.contributor.authorCarvalho, Sonia
dc.contributor.authorHenrique, Rui
dc.contributor.authorSelifonov, Alexey
dc.contributor.authorOliveira, Luís
dc.contributor.authorTuchin, Valery V.
dc.date.accessioned2022-02-24T12:21:15Z
dc.date.embargo2031
dc.date.issued2021
dc.description.abstractIn this paper, we describe the combination of ultraviolet (UV) spectroscopy with the optical clearing technique to induce new tissue windows, evaluate their efficiency, study the diffusion properties of agents and discriminate cancer. The use of highly concentrated glycerol solutions has induced high efficiency clearing effects in the UV, both in human colorectal and gingival tissues. The protein dissociation rate obtained for colorectal tissues was approximately 3 times higher in pathological than in normal mucosa and the kinetics of diffuse reflectance in the UV allowed to estimate the diffusion coefficient for water in gingival mucosa at glycerol action as (1.78 ± 0.26) × 10 -6 cm 2 /s.pt_PT
dc.description.sponsorshipThe authors are grateful to Dr. Yanmei Liang from the Institute of Modern Optics, Nankai Univ. (China) for providing data on the optical thickness of healthy human gingival tissue layers.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationCarneiro, I., Carvalho, S., Henrique, R., Selifonov, A., Oliveira, L. Tuchin, V.V. Enhanced ultraviolet spectroscopy by optical clearing for biomedical applications. IEEE J. Sel. Top. Quant. Elect., vol. 27, no. 4, 7200108. doi: 10.1109/JSTQE.2020.3012350pt_PT
dc.identifier.doi10.1109/JSTQE.2020.3012350pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.22/20056
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherIEEEpt_PT
dc.relation.publisherversionhttps://ieeexplore.ieee.org/document/9153126pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectBiological tissuespt_PT
dc.subjectCancerpt_PT
dc.subjectInduced tissue windowspt_PT
dc.subjectOptical clearingpt_PT
dc.subjectUltraviolet spectroscopypt_PT
dc.titleEnhanced Ultraviolet Spectroscopy by Optical Clearing for Biomedical Applicationspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage8pt_PT
oaire.citation.issue4pt_PT
oaire.citation.startPage1pt_PT
oaire.citation.titleIEEE Journal of Selected Topics in Quantum Electronicspt_PT
oaire.citation.volume27pt_PT
person.familyNameOliveira
person.givenNameLuís
person.identifier414820
person.identifier.ciencia-idC312-F342-BD23
person.identifier.orcid0000-0003-0667-3428
person.identifier.ridB-7198-2017
person.identifier.scopus-author-id55853723900
rcaap.rightsclosedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication4e2de4d7-142a-400f-8dbf-cd0ff9551093
relation.isAuthorOfPublication.latestForDiscovery4e2de4d7-142a-400f-8dbf-cd0ff9551093

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
ART_CIETI_2021.pdf
Size:
2.63 MB
Format:
Adobe Portable Document Format
Download

Collections

ISEP – CIETI – Artigos