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UV-NIR efficiency of the refractive index matching mechanism on colorectal muscle during treatment with different glycerol osmolarities

2020Journal article Open access
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dc.contributor.authorGomes, Nelma
dc.contributor.authorTuchin, Valery V.
dc.contributor.authorOliveira, Luís
dc.date.accessioned2021-05-07T14:30:28Z
dc.date.available2021-05-07T14:30:28Z
dc.date.issued2020
dc.description.abstractThe evaluation of the optical clearing mechanisms in tissues provides information about the efficiency of the clearing treatment. One of such mechanisms is the refractive index matching, which is created by the partial replacement of tissue water by an optical clearing agent with higher refractive index, better matched to the index of tissue scatterers. With the objective of evaluating the refractive index matching mechanism for a wide spectral range and comparing its magnitude between treatments with different clearing agent osmolarities, thickness and collimated transmittance measurements were obtained from human colorectal muscle samples under treatment with 20%-, 40% and 60%-glycerol. Such measurements were used in a calculation model to obtain the refractive index kinetics for the interstitial fluid and for the whole tissue. The calculation results show that the refractive index matching has a stronger effect in the ultraviolet and that such matching is more effective for higher agent concentrations in the treating solutions.pt_PT
dc.description.sponsorshipThis research was supported by the Portuguese Grant FCT UIDB/04730/2020. VVT was supported by the grant of the Russian Foundation of Basic Research #18-29-02060 MK.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.18287/JBPE20.06.020307pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.22/17916
dc.language.isoengpt_PT
dc.publisherSamara Universitypt_PT
dc.relationCenter for Innovation in Industrial Engineering and Technology
dc.relation.publisherversionhttp://jbpe.ssau.ru/index.php/JBPE/article/view/3374pt_PT
dc.subjectUltraviolet spectroscopypt_PT
dc.subjectRefractive index matchingpt_PT
dc.subjectLight scatteringpt_PT
dc.subjectTissue water contentpt_PT
dc.subjectOptical clearingpt_PT
dc.subjectColorectal musclept_PT
dc.subjectCollimated transmittancept_PT
dc.titleUV-NIR efficiency of the refractive index matching mechanism on colorectal muscle during treatment with different glycerol osmolaritiespt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleCenter for Innovation in Industrial Engineering and Technology
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04730%2F2020/PT
oaire.citation.endPage13pt_PT
oaire.citation.issue2pt_PT
oaire.citation.startPage1pt_PT
oaire.citation.titleJournal of Biomedical Photonics & Engineeringpt_PT
oaire.citation.volume6pt_PT
oaire.fundingStream6817 - DCRRNI ID
person.familyNameOliveira
person.givenNameLuís
person.identifier414820
person.identifier.ciencia-idC312-F342-BD23
person.identifier.orcid0000-0003-0667-3428
person.identifier.ridB-7198-2017
person.identifier.scopus-author-id55853723900
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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relation.isAuthorOfPublication.latestForDiscovery4e2de4d7-142a-400f-8dbf-cd0ff9551093
relation.isProjectOfPublicationcdbfce2f-6ff0-4d59-a7c6-96c99d52a570
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