Percorrer por autor "Pinto, Bernardo Sousa"
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- Allergic rhinitis and work productivity: Preliminary analysis of data from the MASK-air applicationPublication . Ferreira, Laura; Pinto, Bernardo Sousa; Alves, Sandra Maria; Amaral, Rita; Alves, Sandra Maria; Amaral, RitaAllergic rhinitis is a health condition more prevalent in developed countries that can impact the activities and quality of life of affected individuals1. Although its impact on work productivity is recognized2, there is still a need for a more detailed understanding and quantification. This cross-sectional observational study investigates the relationship between allergic rhinitis and work productivity, using data from the MASK-air mobile designed for monitoring allergic rhinitis and related respiratory conditions3. To investigate the association between the severity of allergic rhinitis symptoms and the impact on work productivity. Data was collected through the MASK-air mobile application4,5 that contains demographic, environmental and symptom variables on a daily basis, with users providing information on a scale of 0 to 100 each day. A sample of 1000 random observations of users from 30 countries, recorded between May 2015 and December 2023 was analysed. Participants were selected based on specifics criteria, including a minimum age of 15 or 16 (depending on the digital consent age in each country) and self-reported diagnosis of allergic rhinitis. Descriptive statistics and the Spearman correlation coefficient6 between symptoms and impact on productivity were calculated. The sample showed a balanced distribution between sexes, with 435 individuals identified as female (53.5%) and 378 individuals as male (46.5%). The mean age of participants was 41.41 ± 14.50 years. The data included participants from various countries; the most frequent was from Mexico with 141 participants (17.3%), followed by Lithuania with 91 participants (11.9%), and Germany with 79 participants (9.7%). Regarding comorbidities, 535 participants (65.6%) reported having conjunctivitis, and 310 participants (38.1%) reported being asthmatic. Additionally, 200 participants (20%) used immunotherapy. A strong positive correlation was observed between work impact and the severities of global allergic symptoms (ρs= 0.82, p < 0.0001) and nasal symptoms (ρs= 0.77, p < 0.0001); and a moderate correlation was observed between work impact and the severities of ocular symptoms (ρs= 0.69, p < 0.0001) and asthma (ρs= 0.48, p< 0.0001). This study offers an initial understanding of how symptoms of allergic rhinitis affect work productivity. Identifying other associated factors will allow targeting health interventions and policies to improve the well-being and performance of workers affected by this condition.
- Control of allergic rhinitis and asthma test for children (CARATkids): A systematic review and meta-analysis of its measurement propertiesPublication . Didi, Hadla Sami El; Pereira, Ana Margarida; Jácome, Cristina; Amaral, Rita; Wandalsen, Gustavo F.; Emons, Joyce; Grutta, Stefania La; Cilluffo, Giovanna; Batmaz, Sehra Birgül; Linhares, Daniela; Sole, Dirceu; Pinto, Bernardo Sousa; Fonseca, João Almeida; Vieira, Rafael José; Amaral, RitaControl of Allergic Rhinitis and Asthma Test for Children (CARATkids) is the first patient-reported outcome measure (PROM) designed to assess both allergic rhinitis and asthma simultaneously in children aged 6 to 12 years. CARATkids has been validated in several languages and countries, highlighting the need for a review of its psychometric properties. This study aims to evaluate the measurement properties of CARATkids. This systematic review follows PRISMA and COSMIN guidelines. A systematic search was performed across three databases (Ovid/MEDLINE, Web of Science, and Scopus in October 2023, updated in June 2025). We included studies focused on the development, cultural adaptation, or validation of CARATkids, as well as studies comparing CARATkids with other PROMs. We evaluated the quality of CARATkids development, the methodological quality of primary studies, the overall rating, and the certainty of evidence for each CARATkids measurement property and performed a meta-analysis of its measurement properties. Our search retrieved 193 results. We included nine studies. CARATkids displayed sufficient content validity. Regarding internal consistency, we found a meta-analytical Cronbach alpha of 0.81 (95% CI = 0.79; 0.83). CARATkids displayed sufficient reliability (meta-analytical intraclass correlation coefficient 0.86 [95% CI = 0.61; 0.96]). The minimal clinically important difference was 2.76. Construct validity had sufficient evidence for most correlations, with absolute meta-analytical Spearman coefficients from 0.37 to 0.71. Responsiveness showed strong correlations between CARATkids and most outcome measurement instruments. These findings support CARATkids as a suitable tool for assessing asthma and allergic rhinitis in children aged 6 to 12 years who present both conditions simultaneously.