Browsing by Author "Petrovski, eljko"
Now showing 1 - 3 of 3
Results Per Page
Sort Options
- Bioactivity of ionic liquids based on valproate in the human osteoclastogenesisPublication . Correia, Joana; Ferraz, Ricardo; Costa-Rodrigues, João; Fernandes, Maria Helena; Branco, Luís C.; Noronha, João Paulo; Petrovski, eljko; Prudêncio, CristinaIonic Liquids (ILs) are salts (with at least one organic cation), that have a melting point lower than 100º C. The interest in these compounds has been increasing as well as the number of applications where they can be used. Their first applications were on batteries and in organic synthesis and soon they started to be applied on health sciences. With this work we intend to study the biological properties of ILs based on valproate, and evaluate their modulation potential on human osteoclastogenesis.
- Biological activity of ionic liquids based on bis-pyridinium in Gram-positive and Gram- negative bacteriaPublication . Ferreira, Joana; Ferraz, Ricardo; Vieira, Mónica; Fernandes, Rúben; Branco, Luís C.; Noronha, João Paulo; Petrovski, eljko; Prudêncio, CristinaResistance to antibiotics is becoming a public health problem and is the subject of concern from various global entities. In this context, finding new alternatives to combat microbial infections is critical. Ionic liquids (ILs) come up as a resource to be used in the pharmaceutical industry, especially in the synthesis of new antibiotics. The ILs have shown the ability to improve the characteristics of active pharmaceutical ingredients. However this is not the only the relevance of these compounds, antimicrobial properties also have been described. The bis-pyridinium ILs are now being studied as antimicrobial agents in the present study.
- Study the activity of cetylpyriridinium cmpicilin on resistant and sensitive Escherichia coliPublication . Oliveira, Sofia; Ferraz, Ricardo; Vieira, Mónica; Fernandes, Rúben; Branco, Luís C.; Noronha, João Paulo; Petrovski, eljko; Prudêncio, CristinaIonic Liquids (ILs) are organic salts with melting point below 100 ºC. Their possible combinations anion/cation render them more suitable for several biological applications. Understand the activity of cetylpyriridinium ampicillin on sensitive and resistant Escherichia coli.